- 2-Thiopheneethylamine
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- $0.00 / 1kg
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2023-09-18
- CAS:30433-91-1
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20tons
- Thiophene-2-ethylamine
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- $67.00 / 1kg
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2023-04-25
- CAS:30433-91-1
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5000 tons
- Thiophene-2-ethylamine
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- $50.00 / 1KG
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2023-01-31
- CAS:30433-91-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20tons
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| | Thiophene-2-ethylamine Basic information |
| | Thiophene-2-ethylamine Chemical Properties |
| Melting point | 202 °C | | Boiling point | 200-201 °C/750 mmHg (lit.) | | density | 1.087 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.551(lit.) | | Fp | 190 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO, Methanol | | pka | 9.47±0.10(Predicted) | | form | Liquid | | Specific Gravity | 1.087 | | color | Colorless to yellow | | Sensitive | Air Sensitive | | BRN | 106962 | | InChIKey | HVLUYXIJZLDNIS-UHFFFAOYSA-N | | CAS DataBase Reference | 30433-91-1(CAS DataBase Reference) |
| Hazard Codes | Xn,Xi | | Risk Statements | 20/21/22-36/37/38 | | Safety Statements | 26-36-37/39 | | RIDADR | NA 1993 / PGIII | | WGK Germany | 3 | | HazardClass | IRRITANT | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29339900 |
| | Thiophene-2-ethylamine Usage And Synthesis |
| Chemical Properties | A colorless to yellow liquid with unstable properties requiring protection with nitrogen gas. It appears as a light yellow clear liquid, but turns red upon prolonged exposure. | | Uses | [2-(Thiophene-2-yl)ethyl]amine is used in the synthesis of geldanamycin derivatives as HCV replication inhibitors targetting Hsp90. | | Uses | 2-Thiopheneethylamine (2-thiophene ethyl amine, 2-(thien-2-yl)ethylamine) is suitable to functionalize multiwall carbon nanotubes (MWCNT).
It may be used as a reactant in the synthesis of pyrimidine derivatives by reacting with various isothiocyanatoketones and acylguanidines derivatives by reacting with aroyl S-methylisothiourea. | | General Description | 2-Thiopheneethylamine (2-(thiophen-2-yl)ethanamine) is an aromatic amine. It undergoes microwave induced condensation with iminodiacetic acid to form the corresponding piperazine-2,6-dione derivatives. Its effect as a probable substitute to the pyridine ligand on the performance of poly(3-hexylthiophene)/CdSe hybrid solar cells has been investigated. | | Synthesis | N,N-Dimethylformamide (DMF) reacts with thiophene to obtain 2-thiophenecarbaldehyde, then reacts with isopropyl chloroacetate to obtain 2-thiopheneacetaldehyde, and then reacts with hydroxylamine hydrochloride to obtain 2-thiopheneacetaldehyde oxime, and finally reduced to give 2-thiopheneethylamine. | | References | [1] M. BARWIOLEK. Structural and spectral studies of silver(I) complexes with new Schiff bases derived from 2-thiopheneethylamine and their application in thin layer deposition by spin and dip coating techniques[J]. Polyhedron, 2017, 124: Pages 12-21. DOI:10.1016/j.poly.2016.12.011.
[2] BHUSHAN D. VARPE S B J. Schiff Base of Isatin with 2-Thiopheneethylamine and Its Mannich Bases: Synthesis, Docking, and In Vitro Anti-Inflammatory and Antitubercular Activity[J]. Russian Journal of Bioorganic Chemistry, 2022, 48 2: 372-379. DOI:10.1134/S1068162022020030.
[3] JUN YAN LEK. Understanding the Effect of Surface Chemistry on Charge Generation and Transport in Poly (3-hexylthiophene)/CdSe Hybrid Solar Cells[J]. ACS Applied Materials & Interfaces, 2011, 3 2: 287-292. DOI:10.1021/am100938f.
[4] SANDEEP KUMAR. Efficient synthesis of piperazine-2,6-dione and 4-(1H-indole-2-carbonyl)piperazine-2,6-dione derivatives and their evaluation for anticancer activity[J]. Medicinal Chemistry Research, 2013, 22 10: 4600-4609. DOI:10.1007/s00044-012-0438-7. |
| | Thiophene-2-ethylamine Preparation Products And Raw materials |
| Raw materials | Hydrochloric acid-->Methanol-->Tetrahydrofuran-->Dichloromethane-->Potassium hydroxide-->Lithium Aluminum Hydride-->Nitromethane-->Chlorotrimethylsilane-->2-Thiophenecarboxaldehyde-->Lithium borohydride-->Acetaldoxime-->Isopropyl chloroacetate | | Preparation Products | 4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride-->5-(2-AMINOETHYL)THIOPHENE-2-SULFONAMIDE-->Clopidogrel hydrogen sulfate-->5,6,7,7a-Tetrahydro-5-(triphenylmethyl)thieno[3,2-c]pyridinone-->2-Thiopheneacetonitrile-->Thieno[3,2-c]pyridine, 4-(5-chloro-2-thienyl)-4,5,6,7-tetrahydro- |
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