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3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-ol, 37-phenyl- Suppliers list
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3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-ol, 37-phenyl- manufacturers
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| | 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-ol, 37-phenyl- Basic information |
| Product Name: | 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-ol, 37-phenyl- | | Synonyms: | 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-ol, 37-phenyl-;35-benzyloxy-3,6,9,12,15,18,21,24,27,30,33-undecaoxa-pentatriacontan-1-ol;HO-(CH2CH2O)12-Bn;OBn-PEG12-OH;BnO-PEG12-OH | | CAS: | 2218463-17-1 | | MF: | C31H56O13 | | MW: | 636.77 | | EINECS: | | | Product Categories: | | | Mol File: | 2218463-17-1.mol |  |
| | 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-ol, 37-phenyl- Chemical Properties |
| Boiling point | 662.2±50.0 °C(Predicted) | | density | 1.105±0.06 g/cm3(Predicted) | | pka | 14.36±0.10(Predicted) |
| | 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-ol, 37-phenyl- Usage And Synthesis |
| Uses | Benzyl-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | Biological Activity | Benzyl-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | IC 50 | PEGs | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-ol, 37-phenyl- Preparation Products And Raw materials |
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