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Isoniazid

Isoniazid Suppliers list
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Email: Abel@chembj.com
Products Intro: Product Name:Isoniazid
CAS:54-85-3
Purity:99% Package:124/KG
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Isoniazid
CAS:54-85-3
Purity:99.00% Package:100g,500g,1KG,10KG,100KG
Company Name: Shanghai Bojing Chemical Co.,Ltd.
Tel: +86-21-37122233
Email: Candy@bj-chem.com
Products Intro: Product Name:Isoniazid
CAS:54-85-3
Purity:99% Package:1kg;25kg;200kg Cardboard barrels Remarks:crystalline
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:54-85-3
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Email: sales@mainchem.com
Products Intro: Product Name:Isoniazid
CAS:54-85-3

Lastest Price from Isoniazid manufacturers

  • Isoniazid
  • US $1.00 / KG
  • 2018-08-21
  • CAS:54-85-3
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 100KG
Isoniazid Basic information
Product Name:Isoniazid
Synonyms:4-PYRIDINECARBOHYDRAZIDE;4-PYRIDINECARBOXYLIC ACID HYDRAZIDE;AKOS BBS-00004103;HYCOZID;LABOTEST-BB LT00146690;INAH;ISONICOTINIC ACID HYDRAZIDE;ISONIAZIDE
CAS:54-85-3
MF:C6H7N3O
MW:137.14
EINECS:200-214-6
Product Categories:NYDRAZID;Antituberculotic;AMIDE;Amines;Aromatics;API;-;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:54-85-3.mol
Isoniazid Structure
Isoniazid Chemical Properties
Melting point 171-173 °C(lit.)
Boiling point 251.97°C (rough estimate)
density 1.2620 (rough estimate)
refractive index 1.6910 (estimate)
Fp >250°C
storage temp. Refrigerator
solubility 125g/l
form Crystals or Crystalline Powder
pkapKa 2.00/3.60/10.8(H2O) (Uncertain)
color White or colorless
PH6-8 (50g/l, H2O, 20℃)
Water Solubility 14 g/100 mL (25 ºC)
Sensitive Air Sensitive
Merck 14,5186
BRN 119374
Stability:Stability Stable, but may be air or light sensitive. Combustible. Incompatible with strong oxidizing agents, chloral, aldehydes, iodine, ferric salts, hypochlorites.
CAS DataBase Reference54-85-3(CAS DataBase Reference)
NIST Chemistry ReferenceIsoniazid(54-85-3)
EPA Substance Registry System4-Pyridinecarboxylic acid, hydrazide(54-85-3)
Safety Information
Hazard Codes Xn
Risk Statements 22-38-40-36/37/38
Safety Statements 37-36/37/39-26
RIDADR 2811
WGK Germany 3
RTECS NS1751850
TSCA Yes
PackingGroup III
HS Code 29333999
Hazardous Substances Data54-85-3(Hazardous Substances Data)
ToxicityLD50 in mice (mg/kg): 151 i.p., 149 i.v. (Jenney, Pfeiffer)
MSDS Information
ProviderLanguage
INAH English
SigmaAldrich English
ACROS English
ALFA English
Isoniazid Usage And Synthesis
Chemical Propertieswhite crystalline powder
Usesantibacterial, tuberculostatic
UsesAntibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Sele ctively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antib acterial (tuberculostatic).
UsesFor the treatment of all forms of tuberculosis in which organisms are susceptible.
DefinitionChEBI: A carbohydrazide obtained by formal condensation between pyridine-4-carboxylic acid and hydrazine.
Brand nameInh (Novartis); Nydrazid (Bristol-Myers Squibb); Nydrazid (Sandoz); Rimifon (Roche).
General DescriptionOdorless colorless or white crystals or white crystalline powder. Taste is slightly sweet at first and then bitter. pH (1% aqueous solution) 5.5-6.5. pH (5% aqueous solution) 6-8.
Air & Water ReactionsSensitive to air and light. Absorbs insignificant amounts of moisture at 77°F at relative humidities up to approximately 90%. Water soluble. Dust can be explosive when suspended in air at specific concentrations.
Reactivity ProfileIsoniazid is incompatible with chloral, aldehydes, iodine, hypochlorites and ferric salts. Isoniazid is also incompatible with oxidizers. Isoniazid may react with sugars and ketones. Isoniazid can react as a weak acid or a weak base. Isoniazid can be decomposed by oxidative and reductive reactions.
Fire HazardIsoniazid is combustible.
Purification MethodsCrystallise isoniazide from 95% EtOH and dry it in a vacuum. [Beilstein 22 III/IV 545, 22/2 V 219.]
Isoniazid Preparation Products And Raw materials
Preparation Products4-ISOCYANATOPYRIDINE
Raw materialsPotassium permanganate-->4-Methylpyridine-->Isonicotinic acid
Tag:Isoniazid(54-85-3) Related Product Information
NIALAMIDE 2-HYDROXY-1-NAPHTHALDEHYDE ISONICOTINOYL HYDRAZONE Ftivazide N'4-[4-(DIMETHYLAMINO)BENZYLIDENE]-2,6-DICHLOROPYRIDINE-4-CARBOHYDRAZIDE Aconiazide 2-ISOPROPYLTHIOXANTHONE Tebufenozide 3,6-Dihydroxypyridazine METHOXYFENOZIDE Ascoric Acid ACETIC ACID Isonicotinic acid 1,5-Diphenylcarbazide Daminozide Formylhydrazine Phthalhydrazide Citric acid Pasiniazid