1,3,4-Oxadiazole, 2-(4-fluorophenyl)-5-[[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]methyl]- manufacturers
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| | 1,3,4-Oxadiazole, 2-(4-fluorophenyl)-5-[[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]methyl]- Basic information |
| Product Name: | 1,3,4-Oxadiazole, 2-(4-fluorophenyl)-5-[[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]methyl]- | | Synonyms: | 1,3,4-Oxadiazole, 2-(4-fluorophenyl)-5-[[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]methyl]-;WAY-637471;2-(4-Fluorophenyl)-5-(((5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)thio)methyl)-1,3,4-oxadiazole;Tuberculosis inhibitor 12 | | CAS: | 793729-44-9 | | MF: | C15H9FN4O3S | | MW: | 344.32 | | EINECS: | | | Product Categories: | | | Mol File: | 793729-44-9.mol | ![1,3,4-Oxadiazole, 2-(4-fluorophenyl)-5-[[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]methyl]- Structure](CAS/20210305/GIF/793729-44-9.gif) |
| | 1,3,4-Oxadiazole, 2-(4-fluorophenyl)-5-[[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]methyl]- Chemical Properties |
| Boiling point | 521.2±60.0 °C(Predicted) | | density | 1.54±0.1 g/cm3(Predicted) | | form | Solid | | pka | -5.78±0.37(Predicted) | | color | Yellow to brown |
| | 1,3,4-Oxadiazole, 2-(4-fluorophenyl)-5-[[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]methyl]- Usage And Synthesis |
| Uses | Tuberculosis inhibitor 12 (compound 12) is an oxadiazole derivative and an inhibitor of Mycobacterium tuberculosis. The inhibition rates of Tuberculosis inhibitor 12 (20 μM) on 7H9-Tw-OADC and 7H9-Tw-OADC reached 82% and 78% respectively[1]. | | References | [1] Early JV, et al. Oxadiazoles Have Butyrate-Specific Conditional Activity against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2016 May 23;60(6):3608-16. DOI:10.1128/AAC.02896-15 |
| | 1,3,4-Oxadiazole, 2-(4-fluorophenyl)-5-[[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]methyl]- Preparation Products And Raw materials |
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