| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:Hepronicate;Hepronicate
CAS:7237-81-2
Purity:98% Package:5 mg
|
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.com |
| Products Intro: |
Product Name:Hepronicate
CAS:7237-81-2
|
| Company Name: |
Leancare Ltd.
|
| Tel: |
+33 962096793 |
| Email: |
enquiry@leancare.co.uk |
| Products Intro: |
|
|
| | Hepronicate Basic information |
| Product Name: | Hepronicate | | Synonyms: | 1,1,1-Heptanetriyltris(methanol) tris(nicotinate);1,1,1-Heptanetriyltris(methanol)tris(nicotinate);2-Hydroxymethyl-2-hexyl-1,3-propanediol trinicotinate;Bis(nicotinic acid)2-hexyl-2-(nicotinoyloxymethyl)-1,3-propanediyl ester;Megrin;Hepronicate;3-Pyridinecarboxylic acid, 1,1'-[2-hexyl-2-[[(3-pyridinylcarbonyl)oxy]methyl]-1,3-propanediyl] ester | | CAS: | 7237-81-2 | | MF: | C28H31N3O6 | | MW: | 505.56 | | EINECS: | | | Product Categories: | | | Mol File: | 7237-81-2.mol |  |
| | Hepronicate Chemical Properties |
| Melting point | 94-96° | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | Hepronicate Usage And Synthesis |
| Originator | Megrin,Yoshitomi,Japan,1972 | | Definition | ChEBI: Hepronicate is an organic molecular entity. | | Manufacturing Process | In 50 ml of pyridine were dissolved 50 grams of nicotinic acid and 50 grams
of p-toluene-sulfonyl chloride. While stirring, the mixture gradually became
hot and colorless, and finally solidified. To the mixture was added dropwise a
solution of 19 grams of 2-hexyl-2-(hydroxymethyl)-1,3-propanediol in 400 ml
of pyridine at a temperature below 80°C. The mixture was heated at 115° to
125°C on an oil bath for 1 hour. After cooling, the mixture was poured into
300 ml of ice water, and extracted with toluene. The toluene layer was washed
in sequence with water, aqueous sodium carbonate and water, dried over
potassium carbonate, and then the toluene was distilled off. The oily residue
was crystallized from ethanol to give 30 grams of 2-hexyl-2-(hydroxymethyl)-
1,3-propanediol trinicotinate, melting at 94° to 96°C. The yield was 59.5%. | | Therapeutic Function | Vasodilator |
| | Hepronicate Preparation Products And Raw materials |
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