| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:NSC 694621
CAS:104857-29-6
Purity:98% Package:5mg Remarks:S89458
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| Company Name: |
Shanghai Chaolan Chemical Technology Center
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| Tel: |
021-QQ：65489617 15618227136 |
| Email: |
Sales@ATKchemical.com |
| Products Intro: |
Product Name:Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-(4-methoxyphenyl)-
CAS:104857-29-6
Purity:98 Package:1G,5G,10G,50G,100G,500G
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Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-(4-methoxyphenyl)- manufacturers
- NSC 694621
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- $53.00 / 2mg
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2025-11-10
- CAS:104857-29-6
- Min. Order:
- Purity: 99.70%
- Supply Ability: 10g
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| | Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-(4-methoxyphenyl)- Basic information |
| | Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-(4-methoxyphenyl)- Chemical Properties |
| Melting point | 164-166 °C(Solv: methanol (67-56-1)) | | Boiling point | 470.6±51.0 °C(Predicted) | | density | 1.381±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 0.74±0.20(Predicted) | | form | Solid | | color | White to off-white |
| | Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-(4-methoxyphenyl)- Usage And Synthesis |
| Description | IC50: 5.71 µM (PCAF/H31-21)[1]. NSC 694621 is a potent PCAF inhibitor, with an IC50 of 5.71 µM (PCAF/H31-21). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells[1]. NSC 694621 (25 µM; 72 h) exhibits antiproliferative effect to SK-N-SH and HCT116 cells[1]. Cell Proliferation Assay[1] | | Uses | NSC 694621 is a potent PCAF inhibitor, with an IC50 of 5.71 μM (PCAF/H31-21). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells[1]. | | References | [1] Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19(12):3678-89. DOI:10.1016/j.bmc.2011.01.063 |
| | Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-(4-methoxyphenyl)- Preparation Products And Raw materials |
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