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| | NEUROTENSIN Basic information |
| Product Name: | NEUROTENSIN | | Synonyms: | 5-Oxo-L-Pro-L-Leu-L-Tyr-L-Glu-L-Asn-L-Lys-L-Pro-L-Arg-L-Arg-L-Pro-L-Tyr-L-Ile-L-Leu-OH;Neurotensin【ox】;Neurotensin【rat】;C01836;GLP-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU;NEUROTENSIN;NEUROTENSIN (1-13);NEUROTENSIN (HUMAN, BOVINE, CANINE) | | CAS: | 55508-42-4 | | MF: | C78H121N21O20 | | MW: | 1672.95 | | EINECS: | | | Product Categories: | Peptide | | Mol File: | 55508-42-4.mol |  |
| | NEUROTENSIN Chemical Properties |
| density | 1.46±0.1 g/cm3(Predicted) | | storage temp. | -15°C | | pka | 3.41±0.10(Predicted) |
| | NEUROTENSIN Usage And Synthesis |
| Definition | ChEBI: Neurotensin is a 13 amino acid peptide hormone which is found in the central nervous system and the gastrointestinal tract. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinson's disease, drug abuse, pain, cancer, inflammation, eating disorders and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems such as dopaminergic, sertonergic, glutamatergic, GABAergic, and cholinergic systems. It has a role as a human metabolite, a mitogen, a neurotransmitter and a vulnerary. It is a conjugate base of a neurotensin(1+). | | General Description | Neurotensin is a 13-amino-acid peptide, first isolated frombovine hypothalamus. It has now been identified in the intestinaltract. The ileal mucosa contains 90% of the total neurotensinof the body. It is implicated as a releasing factor forseveral adenohypophyseal hormones. It causes vasodilatation,increases vascular permeability, and increases gastrinsecretion. It decreases secretion of gastric acid and secretin. |
| | NEUROTENSIN Preparation Products And Raw materials |
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