| Company Name: |
Nantong Hanfang Biotechnology Co. , Ltd.
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| Tel: |
hanfangpharma@126.com; 18616537568 |
| Email: |
hanfangpharma@126.com |
| Products Intro: |
Product Name:1,8-Naphthyridine-3-carbonitrile, 7-(3-chloro-2-fluoro-6-hydroxyphenyl)-6-fluoro-1,2-dihydro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-2-oxo-4-[4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-
CAS:2650550-87-9
Purity:98%+ Package:1g；5g；10g；100g; 1kg
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:KRAS G12C inhibitor 35
CAS:2650550-87-9
Package:100mg/RMB 25500;25mg/RMB 15000;50mg/RMB 19800
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1,8-Naphthyridine-3-carbonitrile, 7-(3-chloro-2-fluoro-6-hydroxyphenyl)-6-fluoro-1,2-dihydro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-2-oxo-4-[4-(1-oxo-2-propen-1-yl)-1-piperazinyl]- manufacturers
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| | 1,8-Naphthyridine-3-carbonitrile, 7-(3-chloro-2-fluoro-6-hydroxyphenyl)-6-fluoro-1,2-dihydro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-2-oxo-4-[4-(1-oxo-2-propen-1-yl)-1-piperazinyl]- Basic information |
| | 1,8-Naphthyridine-3-carbonitrile, 7-(3-chloro-2-fluoro-6-hydroxyphenyl)-6-fluoro-1,2-dihydro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-2-oxo-4-[4-(1-oxo-2-propen-1-yl)-1-piperazinyl]- Chemical Properties |
| Boiling point | 760.7±60.0 °C(Predicted) | | density | 1.47±0.1 g/cm3(Predicted) | | pka | 6.11±0.48(Predicted) |
| | 1,8-Naphthyridine-3-carbonitrile, 7-(3-chloro-2-fluoro-6-hydroxyphenyl)-6-fluoro-1,2-dihydro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-2-oxo-4-[4-(1-oxo-2-propen-1-yl)-1-piperazinyl]- Usage And Synthesis |
| Uses | KRAS G12C inhibitor 35 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 35 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent CN112920183A, compound 3)[1]. | | References | [1] Liwen Zhao, et al. Compounds as kras-g12c inhibitors and their applications. Patent CN112920183A. |
| | 1,8-Naphthyridine-3-carbonitrile, 7-(3-chloro-2-fluoro-6-hydroxyphenyl)-6-fluoro-1,2-dihydro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-2-oxo-4-[4-(1-oxo-2-propen-1-yl)-1-piperazinyl]- Preparation Products And Raw materials |
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