paraherquamide

paraherquamide Suppliers list
Company Name: BOC Sciences
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Products Intro: Product Name:Paraherquamide A
CAS:77392-58-6
Purity:>95% by HPLC Remarks:Paraoxamide A is a mycotoxin derived from the fungus Penicillium. Paraherquamide A is a selective, competitive, cholinergic antagonist that distinguishes subtypes of cholinergic receptors. The structu
Company Name: Hangzhou Verychem Science And Technology Co.Ltd
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Products Intro: Product Name:Paraherquamide A
CAS:77392-58-6
Purity:99% Package:5KG;1KG:10KG:25kg
Company Name: Lynnchem  
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Products Intro: Product Name:paraherquamide
CAS:77392-58-6
Purity:>95% by HPLC Package:1mg;5mg
Company Name: Novachemistry  
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Products Intro: Product Name:Paraherquamide A
CAS:77392-58-6
Purity:>95% by HPLC Package:1mg;5mg
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
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Products Intro: Product Name:Paraherquamide A
CAS:77392-58-6
Purity:>98% Package:1mg;10mg;50mg;100mg;
paraherquamide Basic information
Product Name:paraherquamide
Synonyms:paraherquamide;VM 29919;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizine]-9,10'(10H)-dione, 2',3',8'a,9'-tetrahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-
CAS:77392-58-6
MF:C28H35N3O5
MW:493.59
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Mol File:77392-58-6.mol
paraherquamide Structure
paraherquamide Chemical Properties
Melting point 244-247° (dec)
alpha D22 -28° (c = 0.43 in methanol)
form White to off-white powder.
Safety Information
MSDS Information
paraherquamide Usage And Synthesis
DescriptionParaherquamide A is a mycotoxin anthelmintic originally isolated from P. paraherquei. It binds to acetylcholine receptors (IC50 = 0.5 nM for head homogenates of M. domestica) and acts as an antagonist. Paraherquamide A is toxic to C. elegans (LD50 = 2.5 μg/ml) and effective against T. colubriformis infection in gerbils when used at doses ranging from 0.39 to 200 mg/kg. It is toxic to mice (LD50 = 14.9 mg/kg).
UsesParaherquamide A is a selective, competitive, cholinergic antagonist.
UsesParaherquamide A was first reported as a mycotoxin related to the indole tremorgenic mycotoxins. Subsequent research identified a potent, non-toxic paralysis of nematodes which led to the metabolite's development as a candidate anthelmintic. Paraherquamide A is a selective, competitive, cholinergic antagonist that distinguishes subtypes of cholinergic receptors.
paraherquamide Preparation Products And Raw materials
Tag:paraherquamide(77392-58-6) Related Product Information
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