| Company Name: |
Shanghai Chaolan Chemical Technology Center
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021-QQ：65489617 15618227136 |
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Sales@ATKchemical.com |
| Products Intro: |
Product Name:N,N-dimethyl-2-((3-phenylquinolin-2-yl)thio)ethanamine
CAS:85273-95-6
Purity:98% Package:50MG;100MG,1G,5G,100G
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| Company Name: |
Shanghai Dongyang Biotechnology Co., Ltd.
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| Tel: |
0512-0512-13601744364 13601744364 |
| Email: |
chemsharker@126.com |
| Products Intro: |
Product Name:N,N-dimethyl-2-((3-phenylquinolin-2-yl)thio)ethanamine
CAS:85273-95-6
Purity:98% Package:1g 5g 10g 25g 50g 100g
|
2-((2-(dimethylamino)ethyl)thio)-3-phenylquinoline manufacturers
- ZM 169369
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- $2500.00 / 100mg
-
2024-10-28
- CAS:85273-95-6
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 2-((2-(dimethylamino)ethyl)thio)-3-phenylquinoline Basic information |
| | 2-((2-(dimethylamino)ethyl)thio)-3-phenylquinoline Chemical Properties |
| Boiling point | 452.0±45.0 °C(Predicted) | | density | 1.17±0.1 g/cm3(Predicted) | | pka | 8.51±0.28(Predicted) |
| | 2-((2-(dimethylamino)ethyl)thio)-3-phenylquinoline Usage And Synthesis |
| Uses | ICI 169369 (free base) is an orally active, selective and non-competitive antagonist against 5HT receptor. ICI 169369 (free base) blunts the vasopressin (AVP), but not the ACTH, prolactin or growth hormone reponses to insulin-induced hypoglycaemia. ICI 169369 (free base) blocks centrally mediated 5-HT responses and lowers portal pressure in portal hypertensive rats[1][2][3][4]. | | References | [1] Thompson CJ, et al. The effects of the specific serotonin antagonist ICI 169,369 on the pituitary hormone response to insulin-induced hypoglycaemia in humans. Clin Endocrinol (Oxf). 1992 Mar;36(3):235-40. DOI:10.1111/j.1365-2265.1992.tb01438.x
[2] Blackburn TP, et al. In vitro studies with ICI 169,369, a chemically novel 5-HT antagonist. Eur J Pharmacol. 1988 Jun 10;150(3):247-56. DOI:10.1016/0014-2999(88)90005-2
[3] Kaumann A J, et al. ICI 169,369 selectively blocks 5-hydroxytryptamine2 receptors and lowers portal pressure in portal hypertensive rats[J]. Gastroenterology, 1988, 95(6): 1601-1606. DOI:10.1016/s0016-5085(88)80084-2
[4] Blackburn TP, et al. Pharmacological studies in vivo with ICI 169,369, a chemically novel 5-HT2/5-HT1C receptor antagonist. Eur J Pharmacol. 1990 May 16;180(2-3):229-37. DOI:10.1016/0014-2999(90)90306-q |
| | 2-((2-(dimethylamino)ethyl)thio)-3-phenylquinoline Preparation Products And Raw materials |
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