| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Daeatal
CAS:103614-28-4
Package:25mg/RMB 20500;50mg/RMB 27300;100mg/RMB 35500
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| | dynorphin A ethylamide (1-9), MeTyr(1)-MeArg(7)-Leu(8)- Basic information |
| | dynorphin A ethylamide (1-9), MeTyr(1)-MeArg(7)-Leu(8)- Chemical Properties |
| | dynorphin A ethylamide (1-9), MeTyr(1)-MeArg(7)-Leu(8)- Usage And Synthesis |
| Description | Dynorphin A ethylamide (1-9), The opioid activities were examined in the bioassays (guinea pig ileum, mouse vas deferens and rabbit vas deferens). the extension of the C-terminal in the peptide chain of [MeArg7,D-Leu8]-Dyn(1-8)-NH2 analogues by Arg is ineffective for increasing the kappa-opioid activities, kappa-receptor selectivity and/or analgesic effects of the peptides. | | Uses | Daeatal (Dynorphin A ethylamide (1-9)) is an ethylamine-modified dynorphin fragment that can be used in the study of analgesia, addiction, depression, etc. Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A can induce neuronal death, and can be used in the research of neurological disease[1]. | | References | [1] Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160(2):361-75. DOI:10.1006/exnr.1999.7235 |
| | dynorphin A ethylamide (1-9), MeTyr(1)-MeArg(7)-Leu(8)- Preparation Products And Raw materials |
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