ALPHA-ELEOSTEARIC ACID manufacturers
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| | ALPHA-ELEOSTEARIC ACID Basic information |
| Product Name: | ALPHA-ELEOSTEARIC ACID | | Synonyms: | ALPHA-ELEOSTEARIC ACID;9(Z),11(E),13(E)-OCTADECATRIENOIC ACID;(9E,11Z,13E)-9,11,13-octadecatrienoic acid;a-EleostearicAcid;(9E,11Z,13E)-9,11,13-Octadecatriensure;(9Z,11E,13E)-9,11,13-Octadecatrienoic acid;C08315;(9Z,11E,13E)-octadeca-9,11,13-trienoic acid | | CAS: | 506-23-0 | | MF: | C18H30O2 | | MW: | 278.43 | | EINECS: | 2080292 | | Product Categories: | | | Mol File: | 506-23-0.mol |  |
| | ALPHA-ELEOSTEARIC ACID Chemical Properties |
| Melting point | 49°C | | Boiling point | 361.24°C (rough estimate) | | density | 0.9028 | | refractive index | 1.5112 | | storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere | | solubility | Aqueous Base (Slightly), Chloroform (Slightly), Methanol (Very Slightly) | | pka | 4.78±0.10(Predicted) | | form | Solid | | color | White to Off-White | | Stability: | Light Sensitive | | InChI | InChI=1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h5-10H,2-4,11-17H2,1H3,(H,19,20)/b6-5+,8-7+,10-9- | | InChIKey | CUXYLFPMQMFGPL-WPOADVJFSA-N | | SMILES | C(O)(=O)CCCCCCC/C=C\C=C\C=C\CCCC |
| | ALPHA-ELEOSTEARIC ACID Usage And Synthesis |
| Uses | α-Eleostearic Acid, is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARγ. | | Definition | ChEBI: (9Z,11E,13E)-octadeca-9,11,13-trienoic acid is a conjugated linolenic acid having three fully-conjugated double bonds at positions 9, 11 and 13, in cis, trans and trans configurations, respectively. | | in vivo | α-Eleostearic acid (0.5% of total lipid given; p.o.) inhibits Sodium Arsenite-induced oxidative stress, including reversal of antioxidant enzyme activity and reduction of lipid peroxidation levels[2].
Oral administration of tung oil, naturally rich inα-Eleostearic acid, to mice limits tumor growth and metastasis in an aggressive TNBC orthotopic xenograft model[3]. |
| | ALPHA-ELEOSTEARIC ACID Preparation Products And Raw materials |
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