Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:BTK-IN-32 CAS:1015441-29-8 Package:50mg;10mg
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| BTK-IN-32 Basic information |
Product Name: | BTK-IN-32 | Synonyms: | BTK-IN-32;Dibenzo[b,f][1,4]thiazepine-8-carboxamide, 10-[(3-chlorophenyl)methyl]-10,11-dihydro-11-oxo-N-[3-[4-(phenylmethyl)-1-piperazinyl]propyl]-, 5-oxide | CAS: | 1015441-29-8 | MF: | C35H35ClN4O3S | MW: | 627.2 | EINECS: | | Product Categories: | | Mol File: | 1015441-29-8.mol |  |
| BTK-IN-32 Chemical Properties |
Boiling point | 821.009±65.00 °C(Press: 760.00 Torr)(predicted) | density | 1.399±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | pka | 14.188±0.20(predicted) |
| BTK-IN-32 Usage And Synthesis |
Uses | BTK-IN-32 (compound C2) is a potent inhibitor of BTK. BTK-IN-32 activates full-length BTK and smaller multidomain BTK fragments instead of the isolated kinase domain[1]. | References | [1] Kueffer LE, et al. Screening and Characterization of Allosteric Small Molecules Targeting Bruton's Tyrosine Kinase. Biochemistry. 2024 Jan 2;63(1):94-106. DOI:10.1021/acs.biochem.3c00362 |
| BTK-IN-32 Preparation Products And Raw materials |
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