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| | QUERCETIN-3-O-GLUCURONIDE Basic information |
| Product Name: | QUERCETIN-3-O-GLUCURONIDE | | Synonyms: | 3,3′,4′,5,7-Pentahydroxyflavone 3-glucuronide;Quercetol 3-O-glucuronide;Quercetol glucuronide;Quercetin 3-glucuronide ,>=99%;Quercetin 3-D-glucuronide;2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl β-D-Glucopyranosiduronic Acid;Mikwelianin;Miquelianin | | CAS: | 22688-79-5 | | MF: | C21H18O13 | | MW: | 478.36 | | EINECS: | | | Product Categories: | Miscellaneous Natural Products | | Mol File: | 22688-79-5.mol |  |
| | QUERCETIN-3-O-GLUCURONIDE Chemical Properties |
| Melting point | 193～195℃ | | Boiling point | 927.8±65.0 °C(Predicted) | | density | 1.96±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 2.76±0.70(Predicted) | | color | Yellow to Very Dark Yellow | | Stability: | Very Hygroscopic | | LogP | 2.100 (est) |
| Safety Statements | 24/25 | | WGK Germany | 3 |
| | QUERCETIN-3-O-GLUCURONIDE Usage And Synthesis |
| Description | Quercetin 3-O-glucuronide is a pharmacologically active flavonol glucuronide isolated from H. perforatum (St. John’s wort) that inhibits the α2c adrenergic receptor (Ki = 4,060 nM in hα2c preparations). Quercetin 3-O-glucuronide (0.6 mg/kg) reduced the time rats spent immobile in the forced swim test, suggesting antidepressant-like properties, when given either acutely or chronically. It also reduced open field stress-induced hyperthermia in mice (at 1.2 mg/kg). | | Chemical Properties | Yellow Solid | | Uses | Quercetin 3-O-β-D-Glucuronide is the major metabolite of Quercetin (Q509500). | | Definition | ChEBI: Miquelianin is a quercetin O-glycoside that consists of quercetin attached to a beta-D-glucuronopyranosyl moiety at position 3 via a glycosidic linkage. Isolated from Salvia and Phaseolus vulgaris, it exhibits antioxidant and antidepressant activities. It has a role as a metabolite, an antioxidant and an antidepressant. It is a beta-D-glucosiduronic acid and a quercetin O-glycoside. |
| | QUERCETIN-3-O-GLUCURONIDE Preparation Products And Raw materials |
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