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Amodiaquin dihydrochloride dihydrate

Amodiaquin dihydrochloride dihydrate Suppliers list
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CAS:6398-98-7
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CAS:6398-98-7
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Amodiaquin dihydrochloride dihydrate manufacturers

  • Amodiaquine HCL
  • Amodiaquine HCL pictures
  • $10.00 / 1kg
  • 2024-04-02
  • CAS:6398-98-7
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 5000 Metric Ton/Month
Amodiaquin dihydrochloride dihydrate Basic information
Product Name:Amodiaquin dihydrochloride dihydrate
Synonyms:Amodiaquine hydrochloride USP24;AMODIAQUINE 2HCL DIHYDRATE;AMODIAQUINE DIHYDROCHLORIDE 2-HYDRATE;AMODIAQUIN DIHYDROCHLORIDE;amodiaquin dihydrochloride dihydrate;AMODIAQUINE DIHYDROCHLORIDE;AMODIAQUINE HCL;AMODIAQUIN HYDROCHLORIDE
CAS:6398-98-7
MF:C20H25Cl2N3O2
MW:410.34
EINECS:642-210-0
Product Categories:CAMOQUIN
Mol File:6398-98-7.mol
Amodiaquin dihydrochloride dihydrate Structure
Amodiaquin dihydrochloride dihydrate Chemical Properties
RTECS GO7300100
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in DMSO or methanol
color White to Yellow to Orange
λmax342nm(MeOH)(lit.)
Merck 14,572
Stability:Hygroscopic
CAS DataBase Reference6398-98-7(CAS DataBase Reference)
Safety Information
WGK Germany 3
HS Code 2933492250
MSDS Information
ProviderLanguage
SigmaAldrich English
Amodiaquin dihydrochloride dihydrate Usage And Synthesis
Chemical PropertiesLight yellow powder
Usesantimalarial
UsesAn anti-malarial quinoline derivative that acts as an histamine N-methyltransferase inhibitor
Brand nameCamoquin (Parke-Davis).
Biological ActivityAmodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.
in vivoIn vivo administration of a small dose amodiaquine dramatically enhanced the effect of histamine on the gastric secretion in dogs. Amodiaquine prevents severe hepatic injury and high lethality in P. acnes-primed and LPS-induced hepatitis mice. Its treatment enhances the elevation of histamine in the liver of P. acnes-primed and LPS-induced hepatitis mice without accompanying tele-methyl histamine elevation.
Amodiaquin dihydrochloride dihydrate Preparation Products And Raw materials
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