- Amodiaquine HCL
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- $10.00 / 1kg
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2024-04-02
- CAS:6398-98-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5000 Metric Ton/Month
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| Amodiaquin dihydrochloride dihydrate Basic information |
Product Name: | Amodiaquin dihydrochloride dihydrate | Synonyms: | Amodiaquine hydrochloride USP24;AMODIAQUINE 2HCL DIHYDRATE;AMODIAQUINE DIHYDROCHLORIDE 2-HYDRATE;AMODIAQUIN DIHYDROCHLORIDE;amodiaquin dihydrochloride dihydrate;AMODIAQUINE DIHYDROCHLORIDE;AMODIAQUINE HCL;AMODIAQUIN HYDROCHLORIDE | CAS: | 6398-98-7 | MF: | C20H25Cl2N3O2 | MW: | 410.34 | EINECS: | 642-210-0 | Product Categories: | CAMOQUIN | Mol File: | 6398-98-7.mol | |
| Amodiaquin dihydrochloride dihydrate Chemical Properties |
RTECS | GO7300100 | storage temp. | Inert atmosphere,Room Temperature | solubility | Soluble in DMSO or methanol | color | White to Yellow to Orange | λmax | 342nm(MeOH)(lit.) | Merck | 14,572 | Stability: | Hygroscopic | CAS DataBase Reference | 6398-98-7(CAS DataBase Reference) |
WGK Germany | 3 | HS Code | 2933492250 |
| Amodiaquin dihydrochloride dihydrate Usage And Synthesis |
Chemical Properties | Light yellow powder | Uses | antimalarial | Uses | An anti-malarial quinoline derivative that acts as an histamine N-methyltransferase inhibitor | Brand name | Camoquin (Parke-Davis). | Biological Activity | Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent. | in vivo | In vivo administration of a small dose amodiaquine dramatically enhanced the effect of histamine on the gastric secretion in dogs. Amodiaquine prevents severe hepatic injury and high lethality in P. acnes-primed and LPS-induced hepatitis mice. Its treatment enhances the elevation of histamine in the liver of P. acnes-primed and LPS-induced hepatitis mice without accompanying tele-methyl histamine elevation. |
| Amodiaquin dihydrochloride dihydrate Preparation Products And Raw materials |
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