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| | Quinine hydrochloride dihydrate Basic information |
| Product Name: | Quinine hydrochloride dihydrate | | Synonyms: | (R)(6-methoxy-4-quinolyl)(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol monohydrochloride dihydrate;Cinchonan-9-ol, 6-methoxy-, monohydrochloride, dihydrate, (8.alpha.,9R)-;QUININEHYDROCHLORIDE,DIHYDRATE,CRYSTAL;Quinine Monohy;Quinine HCl Dihydrate;(8α,9R)-6'-methoxy-cinchonan-9-ol,hydrochloride, hydrate (1:1:2);(8α, 9R)-6′-Methoxycinchonan-9-ol monohydrochloride dihydrate;Quinine monohydrochloride dihydrate Vetec(TM) reagent grade, 88% | | CAS: | 6119-47-7 | | MF: | C20H27ClN2O3 | | MW: | 378.9 | | EINECS: | 612-097-2 | | Product Categories: | API;Alkaloids;Biochemistry;for Resolution of Acids;Optical Resolution;Quinoline Alkaloids;Synthetic Organic Chemistry;AlkaloidAntibiotics;Antibiotics A to;Antibiotics N-SAntibiotics;Spectrum of Activity;Alphabetical Listings;Flavors and Fragrances;Q-Z;chiral;Antiparasitic / Antiprotozoal / AnthelminthicVoltage-gated Ion Channels;Biochemicals Found in Plants;Monovalent Ion Channels;Nutrition Research;Potassium Channel Modulators;Other APIs;Inhibitors;6119-47-7 | | Mol File: | 6119-47-7.mol |  |
| | Quinine hydrochloride dihydrate Chemical Properties |
| Melting point | 115-116 °C (dec.)(lit.) | | alpha | [α]D20 -245～-255° (c=2, dil. HCl) (After Drying) | | bulk density | 310kg/m3 | | FEMA | 2976 | QUININE HYDROCHLORIDE | | refractive index | -250 ° (C=2, EtOH) | | Fp | 122 °C | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | solubility | H2O: soluble0.25/5g/mL, clear, colorless | | form | Crystalline Powder or Silky Needles | | color | White to off-white | | PH | 6.0 (10g/l, H2O, 20℃) | | Odor | odorless | | Odor Type | odorless | | Optical Rotation | [α]22/D 235°, c = 2 in 0.1 M HCl | | Water Solubility | Sparingly soluble in water.(0.26 g/L) (25°C), | | Sensitive | Light Sensitive | | Merck | 14,8061 | | BRN | 6112655 | | InChIKey | MPQKYZPYCSTMEI-HPVDNOPASA-N | | SMILES | O.O.Cl.COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1 | | CAS DataBase Reference | 6119-47-7(CAS DataBase Reference) |
| Hazard Codes | Xn,Xi | | Risk Statements | 22-42/43-36/37/38-20/21/22 | | Safety Statements | 22-36/37-45-36/37/39-26-36 | | RIDADR | 1544 | | WGK Germany | 3 | | RTECS | VA7700000 | | F | 8 | | Hazard Note | Irritant | | HS Code | 29392000 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Resp. Sens. 1
Skin Sens. 1 | | Toxicity | LD50 orally in Rabbit: 620 mg/kg |
| | Quinine hydrochloride dihydrate Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde | | Uses | Quinidine Hydrochloride Dihydrate is a salt of Quinidine (Q685000), a dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial. | | Uses | Antiprotozoal (malaria). |
| | Quinine hydrochloride dihydrate Preparation Products And Raw materials |
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