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| | 8-HYDROXY-7-METHOXYCOUMARIN Basic information |
| Product Name: | 8-HYDROXY-7-METHOXYCOUMARIN | | Synonyms: | 8-HYDROXY-7-METHOXYCOUMARIN;DAPHNETIN-7-METHYL ETHER;DAPHNETIN METHYL ETHER;Daphnetin 7-Methyl ethe;7-Methoxy-8-hydroxy-2H-1-benzopyran-2-one;8-Hydroxy-7-methoxy-2H-1-benzopyran-2-one;7-Methoxy-8-hydroxycoumarin;8-Hydroxy-7-methoxy-2H-chromen-2-one | | CAS: | 19492-03-6 | | MF: | C10H8O4 | | MW: | 192.17 | | EINECS: | 218-290-4 | | Product Categories: | Coumarins | | Mol File: | 19492-03-6.mol |  |
| | 8-HYDROXY-7-METHOXYCOUMARIN Chemical Properties |
| Melting point | 176°C | | Boiling point | 381.9±42.0 °C(Predicted) | | density | 1.377 | | pka | 7.78±0.20(Predicted) | | BRN | 168393 | | LogP | 0.620 (est) |
| Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | HS Code | 2932209090 |
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ALFA
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| | 8-HYDROXY-7-METHOXYCOUMARIN Usage And Synthesis |
| Uses | 8-Hydroxy-7-methoxycoumarin is a phenylpropanoid isolated from the calyxes of Physalis alkekengi L. var. franchetii (Mast.) Makino. 8-Hydroxy-7-methoxycoumarin shows cytotoxicity against GLC4 and COLO 320 cancer cell after continuous incubation (4 days) with IC50s of 179 μM and 145 μM[1][2]. | | Definition | ChEBI: 8-Hydroxy-7-methoxy-2H-1-benzopyran-2-one is a hydroxycoumarin. | | References | [1] HuiLv, et al. Chemical constituents from the calyxes of Physalis alkekengi L. var. franchetii (Mast.) Makino. Biochemical Systematics and Ecology, Volume 78, June 2018, Pages 63-65.
[2] H Kolodzie, et al. Structure-cytotoxicity relationships of a series of natural and semi-synthetic simple coumarins as assessed in two human tumour cell lines. Z Naturforsch C J Biosci. 1997 Mar-Apr;52(3-4):240-4. DOI:10.1515/znc-1997-3-416 |
| | 8-HYDROXY-7-METHOXYCOUMARIN Preparation Products And Raw materials |
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