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Methyl acetoacetate

Methyl acetoacetate Suppliers list
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Products Intro: Product Name:Methyl acetoacetate
CAS:105-45-3
Purity:99% Package:100g,500g,1KG,10KG,100KG
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Products Intro: CAS:105-45-3
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Products Intro: Product Name:Methyl Acetoacetate
CAS:105-45-3
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Products Intro: CAS:105-45-3
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Products Intro: Product Name:Methyl acetoacetate
CAS:105-45-3
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Methyl acetoacetate manufacturers

  • Methyl acetoacetate
  • $50.00 / g
  • 2021-12-02
  • CAS:105-45-3
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 200kg/month
  • Methyl acetoacetate
  • $10.50 / KG
  • 2021-12-01
  • CAS:105-45-3
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 ton
  • Methyl acetoacetate
  • $20.00 / Kg/Drum
  • 2021-11-25
  • CAS:105-45-3
  • Min. Order: 25Kg/Drum
  • Purity: 99.99%
  • Supply Ability: 1 ton per week
Methyl acetoacetate Basic information
Product Name:Methyl acetoacetate
Synonyms:3-OXBUTANOIC ACID METHYL ESTER;3-OXOBUTANOIC ACID METHYL ESTER;3-OXOBUTYRIC ACID METHYL ESTER;ACETYL METHYL ACETATE;ACETOACETIC ACID METHYL ESTER;ACETOACETIC ESTER (METHYL);ACM;HYL ACETOACETATE
CAS:105-45-3
MF:C5H8O3
MW:116.12
EINECS:203-299-8
Product Categories:Building Blocks;C2 to C5;Carbonyl Compounds;Chemical Synthesis;Esters;Organic Building Blocks;Organic synthesis
Mol File:105-45-3.mol
Methyl acetoacetate Structure
Methyl acetoacetate Chemical Properties
Melting point -80 °C (lit.)
Boiling point 169-170 °C/70 mmHg (lit.)
density 1.076 g/mL at 25 °C (lit.)
vapor density 4 (vs air)
vapor pressure 1 hPa (20 °C)
refractive index n20/D 1.419(lit.)
Fp 158 °F
storage temp. 2-8°C
solubility 460 g/L (20°C)
pka10.67±0.46(Predicted)
form Liquid
color APHA: ≤20
PH3.8 (863g/l, H2O, 20℃)
explosive limit1.3-14.2%(V)
Water Solubility 460 g/L (20 ºC)
Merck 14,6009
BRN 506727
InChIKeyWRQNANDWMGAFTP-UHFFFAOYSA-N
CAS DataBase Reference105-45-3(CAS DataBase Reference)
NIST Chemistry ReferenceButanoic acid, 3-oxo-, methyl ester(105-45-3)
EPA Substance Registry SystemMethyl acetoacetate (105-45-3)
Safety Information
Hazard Codes Xi
Risk Statements 36
Safety Statements 26
WGK Germany 1
RTECS AK5775000
Autoignition Temperature536 °F
TSCA Yes
HS Code 29183000
Hazardous Substances Data105-45-3(Hazardous Substances Data)
ToxicityLD50 orally in rats: 3.0 g/kg (Smyth, Carpenter)
MSDS Information
ProviderLanguage
MAA English
SigmaAldrich English
ACROS English
ALFA English
Methyl acetoacetate Usage And Synthesis
Chemical PropertiesColorless, clear liquid
UsesMethyl acetoacetate (MAA) is a starting material for the syntheses of alpha-substituted aceto- acetic esters and cyclic compounds, e.g. pyrazole, pyrimidine and coumarin derivatives.
Uses3-Oxobutanoic Acid Methyl Ester is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.
Production MethodsMethyl acetoacetate is produced by a reaction of methyl acetate with sodium methoxide.
General DescriptionA clear colorless liquid. Flash point 158°F. Denser than water and slightly soluble in water. Vapors heavier than air.
Air & Water ReactionsVery slightly soluble in water.
Reactivity ProfileMethyl acetoacetate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides
HazardToxic by ingestion and inhalation.
Health HazardMay be harmful by inhalation, ingestion, or skin absorption. Causes eye irritation. May cause skin irritation.
Safety ProfileModerately toxic by ingestion. A skin and severe eye irritant. Combustible when exposed to heat or flame. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTERS.
CarcinogenicityNot listed by ACGIH, IARC, NTP, or California Proposition 65.
Tag:Methyl acetoacetate(105-45-3) Related Product Information
Ethoxyamine hydrochloride Isopropyl acetoacetate Acetohydroxamic acid (2-Propenyl) 3-oxobutanoate Methyl 4-oxobutanoate (4-Nitrophenyl)methyl 3-oxobutanoate 2-(METHACRYLOYLOXY)ETHYL ACETOACETATE 2-Methoxyethyl acetoacetate Isobutyl acetoacetate Ethyl acetoacetate tert-Butyl acetoacetate Lithium acetoacetate ACETOACETIC ACID N-BUTYL ESTER Parathion-methyl Acetoxyacetic acid Methyl 4-chloro-3-oxo-butanoate Ethyl 4,4,4-trifluoroacetoacetate ACETYLSALICYLIC ACID METHYL ESTER