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THIQ

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THIQ Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:THIQ
CAS:312637-48-2
Package:1 mL * 10mM (in DMSO)；10 mg；2 mg；25 mg；5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:THIQ
CAS:312637-48-2
Purity:98% Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Aladdin Scientific
Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:THIQ
CAS:312637-48-2
Purity:>=95%(HPLC) Package:$59.9/1mg;Bulk package Remarks:95%(HPLC)
Company Name: J & K SCIENTIFIC LTD.  
Tel: 010-82848833 400-666-7788
Email: jkinfo@jkchemical.com
Products Intro: Product Name:(3R)-N-[(1R)-1-[(4-Chlorophenyl)Methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylMethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxaMide
CAS:312637-48-2
Package:100Mg,25Mg,50Mg
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Email: 3bsc@sina.com
Products Intro: Product Name:THIQ;N-[(1R)-1-[(4-Chlorophenyl)Methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-trazol-1-ylMethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxaMide
CAS:312637-48-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
THIQ Basic information
Product Name:THIQ
Synonyms:3-IsoquinolinecarboxaMide, N-[(1R)-1-[(4-chlorophenyl)Methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylMethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-, (3R)-;(3R)-N-[(1R)-1-[(4-Chlorophenyl)Methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylMethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxaMide;THIQ;N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-trazol-1-ylmethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide;(R)-N-((R)-1-(4-((1H-1,2,4-Triazol-1-yl)methyl)-4-cyclohexylpiperidin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;(3R)-N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidiny;mutant,MC Receptor,inhibit,THIQ,melanocortin,affinity,activity,erectile,selective,eliciting,Melanocortin Receptor,Inhibitor
CAS:312637-48-2
MF:C33H41ClN6O2
MW:589.17
EINECS:
Product Categories:
Mol File:312637-48-2.mol
THIQ Structure
THIQ Chemical Properties
density 1.33±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 250 mg/mL (424.33 mM; Need ultrasonic)
form Powder
pka13.82±0.20(Predicted)
Safety Information
MSDS Information
THIQ Usage And Synthesis
UsesMelanocortin 4 receptors play important roles in the regulation of energy homeostasis, eating behavior and sexual functions (1). (3R)-N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide is a potent and selective melanocortin 4 receptor agonist (2,3). It inhibits parasympathetic preganglionic neurons in the brainstem and regulates sympathetic and parasympathetic preganglionic neurons.
Biological ActivityPotent and selective melanocortin 4 (MC 4 ) receptor agonist (IC 50 values are 1.2, 761 and 2067 nM for human MC 4 , MC 3 and MC 1 receptors respectively). Enhances intracavernosal pressure and stimulates erectile activity in rats ex copula following systemic administration.
storageStore at -20°C
THIQ Preparation Products And Raw materials
Tag:THIQ(312637-48-2) Related Product Information
4-CYCLOHEXYLPIPERIDINE HYDROCHLORIDE 1,2,3,4-Tetrahydroisoquinoline-3-carboxamide 4-(1,2,4-TRIAZOLE-1-YL)-BUTYLAMINE 2-Methylamino-1-morpholin-4-yl-ethanone hydrochloride (R)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID AMIDE THIQ