- Cinchonidine
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- $0.00 / 25KG
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2023-08-30
- CAS:485-71-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
- Cinchonidine
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- $371.00 / 1KG
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2023-06-15
- CAS:485-71-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100kg
- Cinchonidine
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- $0.00 / 1g
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2022-05-11
- CAS:485-71-2
- Min. Order: 10g
- Purity: 99.0%
- Supply Ability: 10tons
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| | Cinchonidine Basic information |
| | Cinchonidine Chemical Properties |
| Melting point | 204-206 °C(lit.) | | alpha | -115 º (c=1, EtOH) | | Boiling point | 436.16°C (rough estimate) | | density | 1.0863 (rough estimate) | | vapor pressure | 0Pa at 25℃ | | refractive index | -107.5 ° (C=1, EtOH) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | 0.25g/l | | form | Crystalline Powder | | pka | 5.80, 10.03(at 25℃) | | color | White to cream | | PH | 9 (0.2g/l, H2O, 20℃) | | optical activity | [α]23/D 109.2°, c = 1.5 in ethanol | | Water Solubility | Insoluble | | Sensitive | Light Sensitive | | Merck | 14,2286 | | BRN | 89690 | | Stability: | Stable, but light-sensitive. Incompatible with strong oxidizing agents. | | InChIKey | KMPWYEUPVWOPIM-NAHPKXJFSA-N | | LogP | 2.68 at 25℃ | | CAS DataBase Reference | 485-71-2(CAS DataBase Reference) | | NIST Chemistry Reference | Cinchonidine(485-71-2) | | EPA Substance Registry System | Cinchonan-9-ol, (8.alpha.,9R)- (485-71-2) |
| | Cinchonidine Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde | | Uses | antiamebic, antiprotozoal | | Uses | Cinchonidine occurs in most varieties of Cinchona bark and is stereoisomeric with Cinchonine. Cinchonidine exhibits Antimalarial properties. | | Definition | ChEBI: 8-epi-Cinchonan in which a hydrogen at position 9 is substituted by hydroxy (R configuration). A diasteroisomer of cinchonine, it occurs in the bark of most varieties of Cinchona shrubs, and is frequently used for
directing chirality in asymmetric synthesis. | | Flammability and Explosibility | Non flammable | | Purification Methods | Crystallise cinchonidine from aqueous EtOH. For the N-benzylcinchonidinium chloride see above entry in this section. [Beilstein 23 III/IV 2824.] |
| | Cinchonidine Preparation Products And Raw materials |
| Preparation Products | (S)-(-)-7,7'-BIS[DI(3,5-DIMETHYLPHENYL)PHOSPHINO]-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE-->(R)-7,7'-BIS(DIPHENYLPHOSPHINO)-1,1'-SPIROBIINDANE-->(S)-1,1'-SPIROBIINDANE-7,7'-DIOL-->(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE-->(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-PHENOXY-->(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-DIMETHYLAMINE-->1,1'-SPIROBIINDANE-7,7'-DIOL-->1,1'-Bis (di-t-butylphosphino)ferrocene palladium dichloride,-->1,1'-Bis(di-tert-butylphosphino)ferrocene-->2-(Dicyclohexylphosphino)biphenyl-->Esfenvalerate-->QUININE SULFATE-->Fosinopril-->Benazepril-->N-Benzylcinchonidinium chloride |
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