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| | 4-(4,4-DiMethyl-2,5-dioxoiMidazolidin-1-yl)-2-trifluoroMethylbenzonitrile Basic information |
| Product Name: | 4-(4,4-DiMethyl-2,5-dioxoiMidazolidin-1-yl)-2-trifluoroMethylbenzonitrile | | Synonyms: | 4-(4,4-DIMETHYL-2,5-DIOXOIMIDAZOLIDIN-1-YL)-2-TRIFLUOROMETHYLBENZONITRILE;Benzonitrile, 4-(4,4-diMethyl-2,5-dioxo-1-iMidazolidinyl)-2-(trifluoroMethyl)-;RU 56279;2-(trifluoromethyl)-4-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)benzonitrile;4-(4,4-Dimethyl-2,5-dioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile;185807 | | CAS: | 143782-20-1 | | MF: | C13H10F3N3O2 | | MW: | 297.23 | | EINECS: | | | Product Categories: | | | Mol File: | 143782-20-1.mol |  |
| | 4-(4,4-DiMethyl-2,5-dioxoiMidazolidin-1-yl)-2-trifluoroMethylbenzonitrile Chemical Properties |
| density | 1.46±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | pka | 7.69±0.70(Predicted) |
| | 4-(4,4-DiMethyl-2,5-dioxoiMidazolidin-1-yl)-2-trifluoroMethylbenzonitrile Usage And Synthesis |
| Uses | 4-(4,4-Dimethyl-2,5-dioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile is an intermediate in the synthesis of Oxo-MDV 3100 (Oxo-enzalutamide) (O857800), which is an impurity of Enzalutamide (M199800), which is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. Enzalutamide has been shown to induce tumor cell apoptosis, and is used for the treatment of castration-resistant prostate cancer. |
| | 4-(4,4-DiMethyl-2,5-dioxoiMidazolidin-1-yl)-2-trifluoroMethylbenzonitrile Preparation Products And Raw materials |
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