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| | 1,1,2-Trimethyl-1H-benz[e]indole Basic information |
| Product Name: | 1,1,2-Trimethyl-1H-benz[e]indole | | Synonyms: | 1,1,2-TRIMETHYL-1H-BENZ(E)INDOLE /2,3,3-TRIMETHYL-4.5-BENZO-3H- INDOLE;2,3,3-TRIMETHYL-4,5-BENZOINDOLENINE(2,3,3-TRIMETHYL-BENZOINDOLENINE)(TBA);2,3,3-Trimethylbenzoeüindolenine, 97%;2,3,3-Trimethyl-4,5-benzoindole;1,2-Trimethyl-1H-benz[e]indole ,98%;1,1,2-Trimethyl-1H-benz[e]indole,96%;1,1,2-Trimethylbenzo[e]indolenine;2-TriMethyl-1H-benz[e]indole | | CAS: | 41532-84-7 | | MF: | C15H15N | | MW: | 209.29 | | EINECS: | 255-429-8 | | Product Categories: | Heterocycle-Indole series;Building Blocks;Heterocyclic Building Blocks;Indoles;IndolesOxindoles;blocks;Indoles and derivatives;electronic;Piperazine derivates | | Mol File: | 41532-84-7.mol | ![1,1,2-Trimethyl-1H-benz[e]indole Structure](CAS/GIF/41532-84-7.gif) |
| | 1,1,2-Trimethyl-1H-benz[e]indole Chemical Properties |
| Melting point | 111-117 °C | | Boiling point | 338.66°C (rough estimate) | | density | 0.7 | | refractive index | 1.5720 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | insoluble (20°C) | | form | Crystalline Powder | | pka | 5.77±0.40(Predicted) | | color | Yellow to brown | | Water Solubility | insoluble (20 ºC) | | BRN | 153709 | | InChI | InChI=1S/C15H15N/c1-10-15(2,3)14-12-7-5-4-6-11(12)8-9-13(14)16-10/h4-9H,1-3H3 | | InChIKey | WJZSZXCWMATYFX-UHFFFAOYSA-N | | SMILES | N1C2=C(C3=CC=CC=C3C=C2)C(C)(C)C=1C | | CAS DataBase Reference | 41532-84-7(CAS DataBase Reference) | | EPA Substance Registry System | 1H-Benz[e]indole, 1,1,2-trimethyl- (41532-84-7) |
| | 1,1,2-Trimethyl-1H-benz[e]indole Usage And Synthesis |
| Chemical Properties | yellow to brown crystalline powder | | Uses | 1,1,2-Trimethyl-1H-benzo[e]indole can be used as an indole pH fluorescent probe and can be used for intracellular pH detection and cell marking. It can also be used as a novel nanocarrier-based near-infrared optical probes for in-vivo tumor imaging. | | Synthesis | Isopropyl methyl ketone (9.00 g, 0.1 mol) was added to a solution of 2-naphthylhydrazine hydrochloride (15.80 g, 0.1 mol) in glacial acetic acid (100 mL). The mixture was stirred for 0.5 h at 20 °C and refluxed for 6 h. Then, the reaction mixture was poured onto ice and neutralized with sodium carbonate, a precipitate formed was collected by filtration. The yield was 19.8 g (95%).
![1,1,2-Trimethyl-1H-benz[e]indole](/NewsImg/2023-12-07/6383755462801426852705277.jpg "1,1,2-Trimethyl-1H-benz[e]indole") |
| | 1,1,2-Trimethyl-1H-benz[e]indole Preparation Products And Raw materials |
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