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DESACETYLVINBLASTINEAMIDE

DESACETYLVINBLASTINEAMIDE Suppliers list
Company Name: Shaanxi Pioneer Biotech Co., Ltd .
Tel: +8613259417953
Email: sales@pioneerbiotech.com
Products Intro: Product Name:Vindesine
CAS:53643-48-4
Purity:0.99 Package:1g;25g;1kg;25kg;100kg
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
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Products Intro: Product Name:DESACETYLVINBLASTINEAMIDE
CAS:53643-48-4
Purity:0.99 Package:5KG;1KG
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: +86-0551-65418671 +8618949823763
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Products Intro: Product Name:vindesine
CAS:53643-48-4
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
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Products Intro: Product Name:DESACETYLVINBLASTINEAMIDE
CAS:53643-48-4
Purity:99.9% Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Products Intro: Product Name:Vindesine
CAS:53643-48-4
Purity:99% Package:5KG;1KG Remarks:Vindesine

DESACETYLVINBLASTINEAMIDE manufacturers

  • Vindesine
  • Vindesine pictures
  • $0.00 / 1Kg
  • 2020-05-03
  • CAS:53643-48-4
  • Min. Order: 1KG
  • Purity: 99.0%
  • Supply Ability: 800 ton
DESACETYLVINBLASTINEAMIDE Basic information
Product Name:DESACETYLVINBLASTINEAMIDE
Synonyms:3-(aminocarbonyl)-o(sup4)-deacetyl-3-de(methoxycarbonyl)-vincaleukoblastin;3-(aminocarbonyl)-o(sup4)-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine;DESACETYLVINBLASTINEAMIDE;Fildesin;Compound 112531:NS C.245467:LY-099094:Hdisine:Fildisin;Vincaleukoblastine, 3-(aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)-;VINDESINE SULFATE(RG);3-(Aminocarbonyl)-O^<4>^-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine
CAS:53643-48-4
MF:C43H55N5O7
MW:753.93
EINECS:258-682-2
Product Categories:
Mol File:53643-48-4.mol
DESACETYLVINBLASTINEAMIDE Structure
DESACETYLVINBLASTINEAMIDE Chemical Properties
Melting point 230-232°
alpha D25 +39.4° (c = 1.0 in methanol)
density 1.41±0.1 g/cm3(Predicted)
pkapKa (DMF 66%) 5.39, 7.36; (H2O) 6.04, 7.67(at 25℃)
Safety Information
RIDADR 1544
HazardClass 6.1(a)
PackingGroup II
Hazardous Substances Data53643-48-4(Hazardous Substances Data)
MSDS Information
DESACETYLVINBLASTINEAMIDE Usage And Synthesis
OriginatorEldisine,Lilly ,France,1980
UsesAntineoplastic.
DefinitionChEBI: Vindesine is a vinca alkaloid, a methyl ester, an organic heterotetracyclic compound, an organic heteropentacyclic compound, a tertiary alcohol, a tertiary amino compound and a primary carboxamide. It has a role as an antineoplastic agent. It is functionally related to a vincaleukoblastine.
Manufacturing ProcessAbout 10 g of VLB (vincaleucoblastine or simply vinblastine) sulfate were converted by standard procedures to VLB free base. The free base, obtained as a residue after evaporation of the dried ethereal solvent, was dissolved in about 200 ml of anhydrous methanol. Anhydrous liquid ammonia (300 ml) was added, and the reaction mixture sealed and maintained at about 100°C for 60 hours. The reaction vessel was opened, and the contents removed and evaporated to dryness in vacuo. The resulting residue, containing 4-desacetyI VLB C-3 carboxamide, as shown by thin layer chromatography, were combined and the solvent evaporated therefrom in vacuo, yielding asa residue purified 4-desacetyl VLB C-3 carboxamide free base. The NMR and IR spectra of the solid free base confirmed the structure indicated. The free base showed a band in the infrared at 1,687 cm -l , characteristic of the amide function. The molecular weight of the free base determined by mass spectroscopy was 753 which is in agreement with theoretical value calculated for C 43 H 55 N 5 O 7 .
Brand nameEldisine (Lilly).
Therapeutic FunctionAntineoplastic
DESACETYLVINBLASTINEAMIDE Preparation Products And Raw materials
Raw materialsMethanol-->Dichloromethane-->Ammonia-->Triphenylphosphine-->HYDRAZINE-->1-Butyl nitrite-->Vinblastine sulfate-->Vincristine sulfate-->VINBLASTINE
Tag:DESACETYLVINBLASTINEAMIDE(53643-48-4) Related Product Information
Vinblastine sulfate Vincristine Dexrazoxane Vinorelbine tartrate Vindesine sulfate 1,3,3,5,5-PENTAMETHYLCYCLOHEXANOL TRIMETHYLHEXAMETHYLENEDIAMINE TRANS-2-AMINOMETHYL-1-CYCLOHEXANOL DESACETYLVINBLASTINEAMIDE P-(TRANS-4-HYDROXYCYCLOHEXYL)PHENOL (2-METHOXY-5-METHYLPHENYL)ACETIC ACID TRANS-2-HYDROXY-1-CYCLOHEXANECARBOXAMIDE CIS-2-AMINO-1-CYCLOHEXANECARBOXAMIDE 1-(2-(2-Methyl-1H-indol-3-yl)ethyl)-3-piperidinol 2-METHOXY-5-METHYL-BENZENEACETIC ACID METHYL ESTER Propionic acid, 2-(4-(isopropylamino)phenyl)- 2-Methyl-3-(2-(3-methyl-1-piperidinyl)ethyl)-1H-indole 2,4-BIS(1-METHYLBUTYL)PHENOL