- Khellin
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- $68.00 / 50mg
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2026-01-24
- CAS:82-02-0
- Min. Order:
- Purity: 99.89%
- Supply Ability: 10g
- Khellin
-
- $68.00 / 50mg
-
2026-01-24
- CAS:82-02-0
- Min. Order:
- Purity: 99.89%
- Supply Ability: 10g
- Khellin
-
- $0.00 / 1KG
-
2020-05-12
- CAS:82-02-0
- Min. Order: 1KG
- Purity: 99.0%
- Supply Ability: 500 MT
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| | KHELLIN Basic information |
| Product Name: | KHELLIN | | Synonyms: | 4,9-DIMETHOXY-7-METHYL-5H-FURO[3,2-G]-[1]BENZOPYRAN-5-ONE;4,9-DIMETHOXY-7-METHYLFURO[3,2-G](1)BENZOPYRAN-5-ONE;2-g)(1)benzopyran-5-one,4,9-dimethoxy-7-methyl-5h-furo(;4,9-dimethoxy-7-methyl-5-oxo-1,8-dioxabenz-(f)indene;ammispasmin;ammivin;ammivisnagen;norkel | | CAS: | 82-02-0 | | MF: | C14H12O5 | | MW: | 260.24 | | EINECS: | 201-392-8 | | Product Categories: | AMIVIN;Herb extract;Inhibitors | | Mol File: | 82-02-0.mol |  |
| | KHELLIN Chemical Properties |
| Melting point | 150154°C | | Boiling point | 180200°C0.05mm Hg | | density | 1.1954 (rough estimate) | | refractive index | 1.4560 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | crystalline | | color | light yellow | | Water Solubility | 247.2g/L(25 ºC) | | Merck | 14,5309 | | BRN | 263185 | | Major Application | food and beverages | | InChI | 1S/C14H12O5/c1-7-6-9(15)10-11(16-2)8-4-5-18-12(8)14(17-3)13(10)19-7/h4-6H,1-3H3 | | InChIKey | HSMPDPBYAYSOBC-UHFFFAOYSA-N | | SMILES | COc1c2OC(C)=CC(=O)c2c(OC)c3ccoc13 | | LogP | 1.770 (est) | | EPA Substance Registry System | Khellin (82-02-0) |
| Hazard Codes | T | | Risk Statements | 25-38-36/37/38-23/24/25 | | Safety Statements | 36/37/39-45-26 | | RIDADR | UN 2811 6.1/PG 3 | | WGK Germany | 3 | | RTECS | LV1050000 | | HS Code | 2932.99.7000 | | HazardClass | 6.1(b) | | PackingGroup | III | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 | | Toxicity | LD50 in mice, rats (mg/kg): 30.6, 34.4 i.v.; 50.8, 68.8 orally (Busch) |
| | KHELLIN Usage And Synthesis |
| Uses | vasodilator (coronary), photosensitizer | | Uses | Khellin has been used as a reference standard for supercritical fluid extraction of khellin from Ammi visnaga L. fruits to understand the various medicinal effects of γ-Pyrones by reversed phase HPLC method. | | Definition | ChEBI: Khellin is a furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator. It has a role as a vasodilator agent, a bronchodilator agent, an anti-asthmatic agent and a cardiovascular drug. It is an organic heterotricyclic compound, an oxacycle and a furanochromone. It is functionally related to a 5H-furo[3,2-g]chromen-5-one. | | Brand name | Ammivin (Marion Merrell Dow); Khelloyd
(Hoechst-Roussel). | | Synthesis Reference(s) | Journal of Medicinal Chemistry, 26, p. 1672, 1983 DOI: 10.1021/jm00366a002 | | General Description | Khellin, is reported to be an efficient drug for treating vitiligo when combined with ultraviolet A irradiation. | | Purification Methods | Crystallise khellin from H2O, MeOH, pet ether or Et2O. The hydrochloride has m 98o(dec) (from EtOH/HCl). [Beilstein 19 II 236, 19 III/IV 2816, 19/6 V 320.] |
| | KHELLIN Preparation Products And Raw materials |
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