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| | 2-Methyl-1,3-cyclopentanedione Basic information |
| | 2-Methyl-1,3-cyclopentanedione Chemical Properties |
| Melting point | 212-215 °C (lit.) | | Boiling point | 213°C (estimate) | | density | 1.0795 (rough estimate) | | refractive index | 1.4550 (estimate) | | storage temp. | Store below +30°C. | | solubility | Solubility in hot Methanol (almost transparency). | | form | Crystalline Powder | | pka | 10.83±0.20(Predicted) | | color | Light beige to tan | | PH | 2.95 at 24.7℃ and 10g/L | | BRN | 1237255 | | InChIKey | HXZILEQYFQYQCE-UHFFFAOYSA-N | | LogP | -0.8 at 30℃ and pH7.66 | | CAS DataBase Reference | 765-69-5(CAS DataBase Reference) | | NIST Chemistry Reference | 1,3-Cyclopentanedione, 2-methyl-(765-69-5) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 22-24/25-36-26 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 29142900 |
| | 2-Methyl-1,3-cyclopentanedione Usage And Synthesis |
| Chemical Properties | LIGHT BEIGE TO TAN CRYSTALLINE POWDER | | Uses | 2-Methyl-1,3-cyclopentanedione hs been used to explore deoxycholic acid (DCA) induced changes in cell signaling. DCA is a secondary bile acid implicated in numerous pathological conditions. It has also been used in the synthesis of (-)-curcumanolide A and (-)-curcumalactone by aldol-lactonization. | | Uses | 2-Methyl-1,3-cyclopentanedione was used as a reactant in the identification and characterization of benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases. | | Synthesis Reference(s) | Synthetic Communications, 19, p. 373, 1989 DOI: 10.1080/00397918908050676 |
| | 2-Methyl-1,3-cyclopentanedione Preparation Products And Raw materials |
| Raw materials | 4-Hydroxy-2-methyl-1,3-cyclopentanedione-->5-Methylcyclopentane-1,2,4-trione-->ethyl 2-(3-methyl-2,4,5-trioxocyclopentyl)-2-oxoacetate-->1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE-->1,3-Cyclopentanedione-->Diphenylmethane-->Fluorene-->Succinic acid-->Acetaldehyde-->Propionyl chloride-->tert-Butyl peroxybenzoate-->Succinic anhydride-->1,1-Dimethoxyethane-->1,4-Cyclohexanedione | | Preparation Products | 2-[2-(6-methoxytetralin-1-ylidene)-ethyl]-2-methylcyclopentane-1,3-dione
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