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| | Ethyl (triphenylphosphoranylidene)acetate Basic information | | Description |
| | Ethyl (triphenylphosphoranylidene)acetate Chemical Properties |
| Melting point | 128-130 °C (lit.) | | Boiling point | 490.4±28.0 °C(Predicted) | | density | 1.086 g/cm3 | | storage temp. | 2-8°C | | solubility | Chloroform, THF | | form | Powder | | color | White to light yellow | | Water Solubility | Insoluble | | Sensitive | Air Sensitive | | BRN | 754639 | | InChI | InChI=1S/C22H21O2P/c1-2-24-22(23)18-25(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21/h3-18H,2H2,1H3 | | InChIKey | IIHPVYJPDKJYOU-UHFFFAOYSA-N | | SMILES | C(OCC)(=O)C=P(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1 | | CAS DataBase Reference | 1099-45-2(CAS DataBase Reference) | | EPA Substance Registry System | Acetic acid, (triphenylphosphoranylidene)-, ethyl ester (1099-45-2) |
| | Ethyl (triphenylphosphoranylidene)acetate Usage And Synthesis |
| Description | Ethyl (triphenylphosphoranylidene)acetate is a common Wittig reagent in organic synthesis as well as a cholinesterase inhibitor that inhibits both AChE and BChE. It is used in the preparation of indole from o-nitrobenzaldehydes, coumarins from o-hydroxy acetophenone.
| | Chemical Properties | Off-White Solid | | Uses | A common Wittig reagent. A cholinesterase inhibitor. | | Uses | (Ethoxycarbonylmethylene)triphenylphosphoran is used as a Wittig reagent in organic synthesis. It is used in the preparation of indole from o-nitrobenzaldehydes, coumarins from o-hydroxy acetophenone. It acts as an inhibitor and inhibits the activity of cholinesterase. | | reaction suitability | reaction type: C-C Bond Formation | | Purification Methods | Crystallise it by dissolving it in AcOH and adding pet ether (b 40-50o) to give colourless plates. UV (A 1% ): 222nm (865) and 268nm (116) [Isler et max 1mm al. Helv Chim Acta 40 1242 1957]. [Beilstein 16 IV 977.] |
| | Ethyl (triphenylphosphoranylidene)acetate Preparation Products And Raw materials |
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