3-O-(2'E,4'E-Decadienoyl)ingenol

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3-O-(2'E,4'E-Decadienoyl)ingenol Basic information
Product Name:3-O-(2'E,4'E-Decadienoyl)ingenol
Synonyms:3-O-(2'E,4'E-Decadienoyl)ingenol;(2E,4E)-2,4-Decadienoic acid (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester;2,4-Decadienoic acid, (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester, (2E,4E)-;4'E-Decadienoyl)ingenol
CAS:466663-11-6
MF:C30H42O6
MW:498.65
EINECS:
Product Categories:
Mol File:466663-11-6.mol
3-O-(2'E,4'E-Decadienoyl)ingenol Structure
3-O-(2'E,4'E-Decadienoyl)ingenol Chemical Properties
Boiling point 635.6±55.0 °C(Predicted)
density 1.20±0.1 g/cm3(Predicted)
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka11.47±0.70(Predicted)
Safety Information
MSDS Information
3-O-(2'E,4'E-Decadienoyl)ingenol Usage And Synthesis
Uses3-O-(2'E,4'E-Decadienoyl)-ingenol is a natural diterpenoid that shows cytotoxicity against human normal cell lines L-O2 and GES-1, with IC50s of 8.22 μM and 6.67 μM, respectively[1].
References[1] Li Zhang, et al. Bio-guided isolation of the cytotoxic terpenoids from the roots of Euphorbia kansui against human normal cell lines L-O2 and GES-1. Int J Mol Sci. 2012;13(9):11247-11259. DOI:10.3390/ijms130911247
3-O-(2'E,4'E-Decadienoyl)ingenol Preparation Products And Raw materials
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