- Nervonic acid
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- $10.00 / 1KG
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2025-11-14
- CAS:506-37-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- Nervonic Acid
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- $0.00 / 25KG
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2025-11-12
- CAS:506-37-6
- Min. Order: 2KG
- Purity: 90% up
- Supply Ability: 20 tons
- Nervonic acid
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- $39.00 / 100mg
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2025-11-10
- CAS:506-37-6
- Min. Order:
- Purity: 99.64%
- Supply Ability: 10g
Related articles - Nervonic acid: Source and Benefits
- Nervonic acid (C24:1 Δ15, cis-15-tetracosenoic acid, NA) is a very long-chain fatty acid whose name originated from the origin....
- Dec 19，2024
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| | Nervonic acid Basic information |
| | Nervonic acid Chemical Properties |
| Melting point | 42-43 °C (lit.) | | Boiling point | 459.84°C (rough estimate) | | density | 0.9009 (rough estimate) | | refractive index | 1.4806 (estimate) | | Fp | >230 °F | | storage temp. | -20°C | | solubility | Chloroform (Slightly), Hexanes (Very Slightly) | | pka | 4.78±0.10(Predicted) | | form | Liquid | | color | White to Pale Yellow | | biological source | plant | | BRN | 1728551 | | InChI | InChI=1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9- | | InChIKey | GWHCXVQVJPWHRF-KTKRTIGZSA-N | | SMILES | C(O)(=O)CCCCCCCCCCCCC/C=C\CCCCCCCC | | LogP | 10.890 (est) | | CAS DataBase Reference | 506-37-6(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | F | 8-10 | | HS Code | 2916.19.3000 |
| | Nervonic acid Usage And Synthesis |
| Description | Nervonic acid, also known as shark oil acid, is a monounsaturated omega-9 fatty acid that exists in nerve tissue and fish oil. It was first discovered in shark brain and is a component of cerebroside, the main source of in shark brain and shark oil. It is also found in the sphingolipids of white matter in human brain. | | Occurrence | Nervonic acid is abundant in King Salmon ( Chinook ) with 140 mg/100g, yellow mustard seed 83 mg/100g , flax seed 64 mg/ 100g, Sockeye salmon 40 mg/100g, sesame seed 35mg/100g, and macademia nuts 18 mg/100g. | | Uses | Neuroic acid is very important in the biosynthesis of nerve cell myelin, which together with lignoceric acid accounts for 60% of the acylated fatty acids in white matter sphingomyelin. In demyelinating diseases such as adrenoleukodystrophy and multiple sclerosis, the amount of neuronic acid acylated to sphingolipids is highly reduced, and supplements rich in this fatty acid have been used to help treat these demyelinating diseases. | | Application | Nervonic acid (NA) is a very-long-chain monounsaturated fatty acid that plays crucial roles in brain development and has attracted widespread research interest. Nervonic acid can be used in nutraceutical, pharmaceutical, and chemical industries. | | Definition | ChEBI: Nervonic Acid is a monounsaturated fatty acid with a 24-carbon backbone and the sole double bond originating from the 9th carbon from the methyl end, with this bond in the cis- configuration. It is a metabolite found in the aging mouse brain. | | Preparation | Nervonic acid was shown to be identical with selachaleic acid isolated from whale oils. It is obvious that nervonic acid is probably the cis form of erucylacetic acid. Erucylacetic acid has been prepared from erucyl alcohol through the bromide and malonic ester synthesis and has been shown to be identical with nervonic acid obtained from hydrolysis of the cerebroside isolated from human brains.
Nervonic acid is also produced from oleic acid, that undergoes three consecutive chain elongation steps, catalyzed by elongases.Two carbon units are added in each step, with production of gadoleic acid, erucic acid, and finally, nervonic acid. | | benefits | Nervonic acid (NA, a monounsaturated long-chain fatty acid) has been found to alleviate neurodegeneration. In humans, abnormal NA levels are closely associated with a higher risk of developing neurological or psychiatric disorders such as psychosis, schizophrenia, or attention deficit disorder. Studies have shown that NA treatment can improve cognitive function, prevent demyelination and oligodendrocyte loss or apoptosis, improve cerebral blood flow, and upregulate brain-derived neurotrophic factor and myelin basic protein genes. In addition, NA can not only stimulate adipogenesis by regulating signaling pathways in human MSCs, but also improve the results of fat transplantation by reducing inflammation and stimulating angiogenesis. | | Biological Functions | Nervonic acid is the only dual-action miracle substance that can repair nerve fibers that unblock damaged nerve pathways in the brain and promote nerve cell regeneration. It has been identified as important in the biosynthesis of nerve cell myelin. It is used in the treatment of disorders involving demyelination, such as adrenoleukodystrophy and multiple sclerosis where there is a decreased level of nervonic acid in sphingolipids. | | General Description | Nervonic acids are the products of desaturation and elongation processes of various fatty acids such as palmitic acid, stearic acid, oleic acid, etc. | | Biochem/physiol Actions | Nervonic acid (C24:1), a component of membrane sphingolipids and phosphatidylethanolamines, may be a useful predictor of chronic kidney disease mortality and diabetes. Nervonic acid oils are being studied for pharmaceutical, nutraceutical and industrial applications. Nervonic acid is a major component of Lunaria oil. | | Source | Sources of Nervonic acid include oil crop seeds, oil-producing microalgae and other microorganisms. Transgenic technology can also be used to improve the source and production of Nervonic acid. |
| | Nervonic acid Preparation Products And Raw materials |
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