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| 4-HYDROXY MEPHENYTOIN Basic information |
| 4-HYDROXY MEPHENYTOIN Chemical Properties |
Melting point | 153-154 °C | density | 1.249±0.06 g/cm3(Predicted) | storage temp. | 2-8°C | solubility | DMSO: >5mg/mL | form | Solid | pka | 8.31±0.70(Predicted) | color | white |
| 4-HYDROXY MEPHENYTOIN Usage And Synthesis |
Chemical Properties | White Solid | Uses | Pharmacological activity investigating:
- The drug effects on metabolization
- In vitro cytochrome P450 activity in microsomes
Analyte for electron-capture gas chromatography procedures | Uses | Pharmacological activity investigating:• ;The drug effects on metabolization1• ;In vitro cytochrome P450 activity in microsomes2Analyte for electron-capture gas chromatography procedures3 | Uses | CYP2C19 metabolite of Mephenytoin | Definition | ChEBI: Hydroxymephenytoin is an imidazolidine-2,4-dione. | General Description | CYP2C19 metabolite of mephenytoin. | Biochem/physiol Actions | 4-Hydroxymephenytoin catabolism displays genetic polymorphism and is a direct indicator of Cytochrome P450 2C19 (CYP2C19) activity. Detection and quantification of 4-hydroxymephenytoin in biological samples by HPLC method is well optimized. |
| 4-HYDROXY MEPHENYTOIN Preparation Products And Raw materials |
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