- Chloropyramine
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- $2500.00 / 100mg
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2025-04-29
- CAS:59-32-5
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Chloropyramine Basic information |
| Product Name: | Chloropyramine | | Synonyms: | 1,2-Ethanediamine, N-[(4-chlorophenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-;2-((p-chlorobenzyl)(2-(dimethylamino)ethyl)amino)-pyridin;2-((p-Chlorobenzyl)(2-(dimethylamino)ethyl)amino)pyridine;Allergan S;n-(p-chlorobenzyl)-n',n'-dimethyl-n-(2-pyridyl)ethylenediamine;CHLOROPYRAMINE BASE;CHLOROPYRAMINE;2-[(4-chlorobenzyl)[2-(dimethylamino)ethyl]amino]pyridine | | CAS: | 59-32-5 | | MF: | C16H20ClN3 | | MW: | 289.8 | | EINECS: | 200-421-1 | | Product Categories: | | | Mol File: | 59-32-5.mol |  |
| | Chloropyramine Chemical Properties |
| Melting point | 25°C | | Boiling point | bp0.2 154-155° | | density | 1.1031 (rough estimate) | | refractive index | 1.6010 (estimate) | | pka | 9.00±0.28(Predicted) | | NIST Chemistry Reference | Chloropyramine(59-32-5) |
| | Chloropyramine Usage And Synthesis |
| Uses | Chloropyramine is used for allergic dermatosis, allergic rhinitis and conjunctivitis, for
drug-induced allergies, in the beginning stages of bronchial asthma, eczema, neurodermatitis,
contact dermatitis, and toxicodermia. It also exhibits a sedative effect. Synonyms
of this drug are suprastin, chlortripelenamine, and synopen. | | Definition | ChEBI: N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridinyl)ethane-1,2-diamine is an aminopyridine. | | Synthesis | Chloropyramine, N-(4-chlorobenzyl)-N??,N??-dimethyl-N-2-pyridylethylenediamine
(16.1.9), is synthesized in a somewhat different manner, which is by reacting
2-brompyridine with N-(4-chlorobenzyl)-N??,N??-dimethylethylenediamine (16.1.8).
N-(4-Chlorobenzyl)-N??,N??-dimethylethylenediamine (16.1.8), in turn, is synthesized by
condensation of 4-chlorobenzaldehyde c N,N-dimethylethylenediamine with subsequent
reduction of the imine group. 
| | in vivo | Chloropyramine (i.p.; 10 mg/kg) abolishes hypothermia in rats[2]. | Animal Model: | Rats[2] | | Dosage: | 10 mg/kg | | Administration: | Intraperitoneal | | Result: | Reduced histamine-induced hypothermia. |
| | IC 50 | H1 Receptor |
| | Chloropyramine Preparation Products And Raw materials |
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