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| | 4-(7-methoxyquinolin-4-yl)-2-methylphenol Basic information |
| Product Name: | 4-(7-methoxyquinolin-4-yl)-2-methylphenol | | Synonyms: | 4-(7-methoxyquinolin-4-yl)-2-methylphenol;CU-CPT-9B, CPD2004;CU-CPT-9b;2-Methyl-4-(7-methoxy-4-quinolinyl)phenol;cas 2165340-32-7;CU-CPT-9B;CAS 2165340-32-7 ;TLR8 INHIBITOR;Phenol, 4-(7-methoxy-4-quinolinyl)-2-methyl-;CU-CPT9a >=98% (HPLC) | | CAS: | 2165340-32-7 | | MF: | C17H15NO2 | | MW: | 265.31 | | EINECS: | | | Product Categories: | | | Mol File: | 2165340-32-7.mol |  |
| | 4-(7-methoxyquinolin-4-yl)-2-methylphenol Chemical Properties |
| Boiling point | 429.7±45.0 °C(Predicted) | | density | 1.201±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml | | form | A crystalline solid | | pka | 8.47±0.20(Predicted) |
| | 4-(7-methoxyquinolin-4-yl)-2-methylphenol Usage And Synthesis |
| Uses | CU-CPT9a is a potent TLR8 inhibitor (IC50 = 0.5 nM and Kd = 21 nM). Stabilizes the TLR8 dimer in its resting state, preventing activation. Suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells. | | storage | Store at -20°C |
| | 4-(7-methoxyquinolin-4-yl)-2-methylphenol Preparation Products And Raw materials |
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