- 4-Chloro-3-fluoroaniline
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- $5.00 / 1KG
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2024-04-08
- CAS:367-22-6
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: g-kg-tons, free sample is available
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| 4-Chloro-3-fluoroaniline Basic information | Uses |
| 4-Chloro-3-fluoroaniline Chemical Properties |
Melting point | 61 | Boiling point | 226°C(lit.) | density | 1.349±0.06 g/cm3(Predicted) | Fp | 60 - 62°C | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | solubility | soluble in Methanol | form | powder to crystal | pka | 2.94±0.10(Predicted) | color | White to Gray to Red | BRN | 2716278 | CAS DataBase Reference | 367-22-6(CAS DataBase Reference) |
| 4-Chloro-3-fluoroaniline Usage And Synthesis |
Uses | 4-Chloro-3-fluoroaniline is used in the synthesis of Methyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate; a key intermediate towards phosphoindole inhibitors of HIV non-nucleoside reverse transcriptase. 4-Chloro-3-fluoroaniline is also used in the synthesis of 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib (D289540) which is an impurity of the tyrosine kinase inhibitor Gefitinib. | Chemical Properties | White to light yellow solid | Uses | 4-Chloro-3-fluoroaniline is used in the synthesis of Methyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate |
| 4-Chloro-3-fluoroaniline Preparation Products And Raw materials |
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