| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
|
| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:1400W dihydrochloride;N-[[3-(AMinoMethyl)phenyl]Methyl]-ethaniMidaMidedihydrochloride
CAS:180001-34-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Ascent Scientific
|
| Tel: |
4401179829988 |
| Email: |
customerservice@ascentscientific.co.uk |
| Products Intro: |
Product Name:1400W
CAS:180001-34-7
Purity:>99% Package:10mg;50mg Remarks:Selective iNOS inhibitor
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:1400W
CAS:180001-34-7
Purity:>98% Remarks:Reach out to us for more information about custom solutions.
|
1400W manufacturers
- 400W
-
- $1.00 / 1KG
-
2019-12-26
- CAS:180001-34-7
- Min. Order: 1KG
- Purity: 97%-99.9%
- Supply Ability: 100kg
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| | 1400W Chemical Properties |
| Melting point | 208-220 °C | | Boiling point | 301.7±44.0 °C(Predicted) | | density | 1.09±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | DMSO, Methanol, Water | | pka | 11.33±0.50(Predicted) | | form | solid | | color | White to Off-White |
| | 1400W Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | A selective inducible nitric oxide synthase (iNOS) inhibitor. A long-acting human iNOS inhibitor possessing an IC50 value of 2.0uM | | Uses | 1400W selectively inhibits inducible nitric oxide synthase. W 1400 has been implicated to prevent Doxorubicin and Trastuzumab induced cardiotoxicity. | | Definition | ChEBI: N-[3-(aminomethyl)benzyl]acetamidine is an aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase. It has a role as an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a geroprotector and an angiogenesis inhibitor. It is a carboxamidine, an aralkylamine and a primary amino compound. | | Biological Activity | Slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (K d = 7 nM). Selective over nNOS and eNOS (K i values are 2 and 50 μ M respectively). Cell-permeable and active in vivo . | | in vivo | 1400W (0.1-10 mg/kg, s.c., once time) inhibits the leakage of rats ileum, with an EC50 of 0.16 mg/kg[1].
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| | 1400W Preparation Products And Raw materials |
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