- Soyasaponin I
-
- $0.00 / 1KG
-
2023-09-06
- CAS:51330-27-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500000kg
- Soyasaponin Bb
-
- $0.00 / 5mg
-
2023-02-24
- CAS:51330-27-9
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
|
| | SOYASAPONIN I Basic information |
| | SOYASAPONIN I Chemical Properties |
| Melting point | 220-222 °C(Solv: methanol (67-56-1)) | | Boiling point | 1024.2±65.0 °C(Predicted) | | density | 1.41 | | storage temp. | 2-8°C | | solubility | ethanol: soluble1mg/mL, clear, colorless | | pka | 2.76±0.70(Predicted) | | form | powder | | color | White | | Stability: | Hygroscopic | | InChIKey | PTDAHAWQAGSZDD-IOVCITQVSA-N |
| WGK Germany | 3 | | HS Code | 29389090 |
| | SOYASAPONIN I Usage And Synthesis |
| Description | Soyasaponin Bb is a triterpenoid saponin that has been found in soy and has enzyme inhibitory, antimetastatic, anti-inflammatory, and neuroprotective biological activities. It selectively inhibits human recombinant and porcine kidney renin (IC50s = 30 and 30 μg/ml, respectively) over bovine trypsin, human urinary kallikrein, and rabbit angiotensin converting enzyme (ACE) when used at a concentration of 100 μg/ml. Soyasaponin Bb inhibits the mouse brain sialyltransferase ST3GAL1 (Ki = 2.1 μM) and decreases levels of α2,3-linked sialic acid on the cell surface and decreases migration of B16/F10 mouse melanoma cells in vitro when used at a concentration of 75 μM. It also dose-dependently increases viability and mRNA expression of heme oxygenase-1 (HO-1) in BRL 3A immortalized rat hepatocytes subjected to alcohol-induced oxidative stress. Soyasaponin Bb (10 mg/kg per day) increases the latency to enter the dark chamber in a passive avoidance test and the percentage of spontaneous alterations in the Y-maze test in a rat model of learning and memory impairment induced by ibotenic acid . | | Uses | Soyasaponin I has been used:
- to test its effect on migration and invasion of ovarian cancer cell lines
- as standard for the quantification of saponins from quinoa and fenugreek samples
- as L-15 medium supplement for Zebrafish liver cell lines
| | Definition | ChEBI: Soyasaponin I is a triterpenoid saponin that is composed of soyasapogenol B having an alpha-L-rhamnopyranosyl-(1->2)-beta-D-galactopyranosyl-(1->2)-beta-D-glucopyranosiduronic acid moiety attached at the 3-position via a glycosidic linkage. It has a role as a sialyltransferase inhibitor. It is a pentacyclic triterpenoid, a triterpenoid saponin, a trisaccharide derivative and a carbohydrate acid derivative. It is functionally related to a soyasapogenol B. It is a conjugate acid of a soyasaponin I(1-). | | General Description | Soyasaponin I is an oleanene-type triterpenoid aglycone and is a group B soyasaponin. It is an amphiphilic molecule and is metabolized by intestinal bacteria into sugars and aglycones. | | Biochem/physiol Actions | Antioxidant and anti-inflammatory saponin found in soybean. Attenuates TNBS-induced colitis in mice. The structure consists of a glycoside moiety and triterpene derivative. Sialytransferase inhibitor and renin inhibitor. |
| | SOYASAPONIN I Preparation Products And Raw materials |
|
|
Tag:SOYASAPONIN I(51330-27-9)
Related Product Information
|
|
Daidzein
6''-O-ACETYLGLYCITIN
Daidzin
Genistin
Glycitin
Soyosaponin Ac
soyosaponin Ab
Soyasaponin Ba
SOYASAPOGENOL A(P)
Soyasaponin Aa
SOYASAPOGENOL B(P)
SOYASAPONIN I
1,1-Dimethoxy-2-(2-methoxyethoxy)ethane
2-[2-(2-METHOXYETHOXY)ETHOXY]ACETIC ACID
C18E3
SOYASAPONIN III
SOYASAPONIN IV
(2S,3S,4S,5R,6R)-6-[[(3S,4S,4aR,6aR,6bS,8aR,9S,12aR,14aS,14bR)-9-hydro xy-4-(hydroxymethyl)-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8 ,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-5-[(2S,3R,4S,5S)-4,5 -dihydroxy-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy -oxan-2-yl]oxy-3,4-dihydroxy-oxane-2-carboxylic acid
|