4-(4-METHOXYPHENOXY)ANILINE manufacturers
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| | 4-(4-METHOXYPHENOXY)ANILINE Basic information |
| | 4-(4-METHOXYPHENOXY)ANILINE Chemical Properties |
| Melting point | 79 °C | | Boiling point | 359.6±27.0 °C(Predicted) | | density | 1.155±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | form | powder | | pka | 4.93±0.10(Predicted) | | color | Charcoal |
| Hazard Codes | Xi | | HazardClass | IRRITANT | | HS Code | 2921420090 |
| | 4-(4-METHOXYPHENOXY)ANILINE Usage And Synthesis |
| Synthesis | Step 2. Synthesis of 4-(4-methoxyphenoxy)aniline
To a solution of 1-methoxy-4-(4-nitrophenoxy)benzene (12.0 g, 49 mmol) in ethyl acetate (EtOAc, 250 mL) was added 5% Pt/C catalyst (1.5 g). The resulting suspension was reacted by shaking under hydrogen atmosphere (50 psi) for 18 hours. Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth (Celite) pad to remove the catalyst. The filtrate was concentrated under reduced pressure to give an oily product, which gradually solidified on standing (10.6 g, 100% yield). The product was characterized by 1H-NMR (CDCl3): δ 3.54 (broad single peak, 2H), 3.78 (single peak, 3H), 6.65 (double peak, J = 8.8 Hz, 2H), 6.79-6.92 (multiple peaks, 6H); EI-MS m/z 215 (M+). | | References | [1] Patent: US2008/269265, 2008, A1. Location in patent: Page/Page column 14
[2] Patent: EP1449834, 2004, A2. Location in patent: Page 22
[3] Patent: EP1042305, 2005, B1. Location in patent: Page/Page column 27
[4] Patent: US2007/244120, 2007, A1. Location in patent: Page/Page column 17
[5] Patent: US2003/207914, 2003, A1. Location in patent: Page/Page column 8 |
| | 4-(4-METHOXYPHENOXY)ANILINE Preparation Products And Raw materials |
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