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Yichang Zhongyitai Trading Co., Ltd.
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0717-6449896 13886658719 |
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| Products Intro: |
Product Name:Sphingosine-1-phosphate (d16:1)
CAS:709026-60-8
Purity:98+% Package:1mg
|
| Company Name: |
Alfa Chemistry
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1-516-6625404 |
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support@alfa-chemistry.com |
| Products Intro: |
Product Name:Sphingosine-1-phosphate (d16:1)
CAS:709026-60-8
Purity:95%+ Package:1g;10g;100g;1KG;5KG
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| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
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sales@glpbio.cn |
| Products Intro: |
Product Name:Sphingosine-1-phosphate (d16:1)
CAS:709026-60-8
Purity:>98% Package:1mg;10mg;50mg;100mg;
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IQHNJQKWEMCXAD-YYZTVXDQSA-N manufacturers
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| | IQHNJQKWEMCXAD-YYZTVXDQSA-N Basic information |
| Product Name: | IQHNJQKWEMCXAD-YYZTVXDQSA-N | | Synonyms: | IQHNJQKWEMCXAD-YYZTVXDQSA-N;Sphingosine-1-phosphate (d16:1);C16-Sphingosine-1-phosphate;4-Hexadecene-1,3-diol, 2-amino-, 1-(dihydrogen phosphate), (2S,3R,4E)- | | CAS: | 709026-60-8 | | MF: | C16H34NO5P | | MW: | 351.42 | | EINECS: | | | Product Categories: | | | Mol File: | 709026-60-8.mol |  |
| | IQHNJQKWEMCXAD-YYZTVXDQSA-N Chemical Properties |
| Boiling point | 528.2±60.0 °C(Predicted) | | density | 1.120±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | 0.3 M NaOH: 4 mg/ml; DMF: <50 μg/ml; DMSO: <50 μg/ml; PBS (pH 7.2): <50 μg/ml | | form | A crystalline solid | | pka | 1.76±0.10(Predicted) |
| | IQHNJQKWEMCXAD-YYZTVXDQSA-N Usage And Synthesis |
| Description | C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate (S1P; ) that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells. C16 S1P was increased in postmortem primary open angle glaucoma trabecular meshwork samples. | | Uses | C16-Sphingosine-1-phosphate is an important regulator of a wide variety of biological processes acting as an endogenous ligand to EDG/S1P receptors. | | Definition | ChEBI: Hexadecasphing-4-enine-1-phosphate is a sphingoid 1-phosphate that is hexadecasphing-4-enine substituted by a phospho group at position 1. It has a role as a mouse metabolite. It is functionally related to a hexadecasphing-4-enine. | | References | [1] HYUN-SUK LIM . Syntheses of sphingosine-1-phosphate analogues and their interaction with EDG/S1P receptors[J]. Bioorganic & Medicinal Chemistry Letters, 2004, 14 10: Pages 2499-2503. DOI: 10.1016/j.bmcl.2004.03.001
[2] AYMAN J ALJOHANI. Human trabecular meshwork sphingolipid and ceramide profiles and potential latent fungal commensalism.[J]. Investigative ophthalmology & visual science, 2014: 3413-3422. DOI: 10.1167/iovs.13-13570 |
| | IQHNJQKWEMCXAD-YYZTVXDQSA-N Preparation Products And Raw materials |
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