Ethyl 3-methyl-1H-pyrazole-5-carboxylate

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Company Name:	ATK CHEMICAL COMPANY LIMITED
Tel:	+undefined-21-51877795
Email:	ivan@atkchemical.com
Products Intro:	Product Name:3-Ethoxycarbonyl-5-methylpyrazole CAS:4027-57-0 Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G

Company Name:	career henan chemical co
Tel:	+86-0371-86658258
Email:	sales@coreychem.com
Products Intro:	Product Name:Ethyl 3-methyl-1H-pyrazole-5-carboxylate CAS:4027-57-0 Purity:99% Package:1KG;2USD

Company Name:	HaBo Hong Kong Co., Limited.
Tel:	+86-25-18512596065
Email:	info@habotech.com
Products Intro:	Product Name:Ethyl 3-methyl-1H-pyrazole-5-carboxylate CAS:4027-57-0 Purity:0.98 Package:based on the requirments Remarks:H

Company Name:	Accela ChemBio Inc.
Tel:	(+1)-858-699-3322
Email:	info@accelachem.com
Products Intro:	Product Name:Ethyl 3-Methylpyrazole-5-carboxylate CAS:4027-57-0 Purity:98% Package:1g;5g;10g;25g;100g Remarks:SY003120

Company Name:	Chengdu Feibo Pharm Technology Co., Ltd
Tel:	15982321820
Email:	abby@arkpharm.com
Products Intro:	Product Name:Ethyl 3-methyl-1h-pyrazole-5-carboxylate CAS:4027-57-0 Purity:97% Package:5g;10g;25g

Ethyl 3-methyl-1H-pyrazole-5-carboxylate manufacturers

Ethyl 3-methyl-1H-pyrazole-5-carboxylate Basic information

Product Name:	Ethyl 3-methyl-1H-pyrazole-5-carboxylate
Synonyms:	ETHYL 3-METHYL-1H-PYRAZOLE-5-CARBOXYLATE;ETHYL 3-METHYL-5-PYRAZOLECARBOXYLATE;ETHYL 3-METHYLPYRAZOLE-5-CARBOXYLATE;ETHYL 5-METHYL-2H-PYRAZOLE-3-CARBOXYLATE;BUTTPARK 29\06-79;AKOS PAO-0427;5-METHYL-2H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER;Ethyl 3-methyl-1h-pyrazole-5-carboxylate, 95+%
CAS:	4027-57-0
MF:	C7H10N2O2
MW:	154.17
EINECS:	223-702-0
Product Categories:	Building Blocks;C7 to C8;Chemical Synthesis;Heterocyclic Building Blocks;Esters;Pyrazoles & Triazoles;Pyrazole;Pyrazoles & Triazoles;Building Blocks;Heterocyclic Building Blocks;Pyrazoles;Pyrazole series;Acids and Derivatives;Heterocycles
Mol File:	4027-57-0.mol

Ethyl 3-methyl-1H-pyrazole-5-carboxylate Chemical Properties

Melting point	80-84 °C (lit.)
Boiling point	299.1±20.0 °C(Predicted)
density	1.171±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
form	powder to crystal
pka	11.60±0.10(Predicted)
color	White to Light yellow
BRN	4192
InChIKey	BOTXQJAHRCGJEG-UHFFFAOYSA-N
CAS DataBase Reference	4027-57-0(CAS DataBase Reference)
NIST Chemistry Reference	3(5)-methyl-5(3)-ethoxycarbonylpyrazole(4027-57-0)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

Ethyl 3-methyl-1H-pyrazole-5-carboxylate Usage And Synthesis

Chemical Properties	White to yellow solid
Uses	Ethyl 3-Methyl-5-pyrazolecarboxylate is a useful synthetic intermediate. It is used to prepare tetrahydroisoquinoline amide substituted Ph pyrazoles as selective Bcl-2 inhibitors. It is also studies as a hypolipidemic agent.
Uses	Ethyl 3-methylpyrazole-5-carboxylate may be used to synthesize the following ligands: potassium salt of new dihydrobis(3-carboxyethyl-5-methylpyrazolyl)borate (Bp^COOEt,Me) [(3-carboxy-5-methyl-1H-1-pyrazolyl) (3-methyl-5-carboxy-1H-1-pyrazolyl)methane, which readily forms Zn(II) and Cd(II) complexes bis(3-carboxy-5-methyl-1H-1-pyrazolyl)methane, which readily forms Zn(II) and Cd(II) complexes
General Description	Ethyl 3-methylpyrazole-5-carboxylate can be prepared by reacting ethyl acetylpyruvate and hydrazine.

Ethyl 3-methyl-1H-pyrazole-5-carboxylate Preparation Products And Raw materials

Raw materials	Ethanol-->Sodium-->Acetone-->Hydrazinium hydroxide solution-->Diethyl oxalate-->Hydrazine monohydrochloride
Preparation Products	4-CHLORO-2,5-DIMETHYL-2H-PYRAZOLE-3-CARBOXYLIC ACID-->5-Methyl-1H-pyrazole-3-carboxylic acid-->1,5-DIMETHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID-->(E)-N-(2,6-dichlorobenzylidene)-3-methyl-1H-pyrazole-5-carbohydrazide-->5-Methyl-3-methanol-1H-pyrazol [1R-(1,2,5)]-->ethyl 3-Methyl-1-propyl-1H-pyrazole-5-carboxylate-->3-Methyl-1-propyl-1H-pyrazole-5-carboxylic acid

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