- Closantel
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- $0.00 / 1kg
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2024-04-07
- CAS:57808-65-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000kg
- Closantel
-
- $10.00 / 1kg
-
2024-03-08
- CAS:57808-65-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000kg
- Closantel
-
- $30.00 / 1kg
-
2023-11-16
- CAS:57808-65-8
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 10 tons
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| Product Name: | Closantel | | Synonyms: | 5-diiodo-y-;benzamide,n-(5-chloro-4-((4-chlorophenyl)cyanomethyl)-2-methylphenyl)-2-hydrox;faskoverm;CLOSANTEL;CLOSANTEL BASE;N-[5-CHLORO-4-(4-CHLORO-ALPHA-CYANOBENZYL)-2-METHYLPHENYL]-2-HYDROXY-3,5-DIIODOBENZAMIDE;n-[5-chloro-4-[(chlorophenyl)cyannomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodobenzamid;iodobenzamide | | CAS: | 57808-65-8 | | MF: | C22H14Cl2I2N2O2 | | MW: | 663.07 | | EINECS: | 260-967-1 | | Product Categories: | COREG CR | | Mol File: | 57808-65-8.mol |  |
| | Closantel Chemical Properties |
| Melting point | 217.8° | | Boiling point | 590.5±50.0 °C(Predicted) | | density | 1.8759 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,2-8°C | | solubility | DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml | | pka | 5.99±0.48(Predicted) | | CAS DataBase Reference | 57808-65-8(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22 | | RIDADR | 2811 | | WGK Germany | 3 | | RTECS | CV2444250 | | HazardClass | 6.1(b) | | PackingGroup | III | | Toxicity | A veterinary drug for the treatment of fluke and
nematode infestations. In 1993, some was included in a batch
of donated drugs sent to Lithuania. Attempts to match the
product with the names of other medicines on accompanying
literature resulted in its misidentification as a treatment for
endometriosis. Eleven women lost their eyesight; though this
has since returned, they were left with eye pain and are unable
to work. |
| | Closantel Usage And Synthesis |
| Description | Closantel is a kind of synthetic anti parasitic agent which is actively against liver fluke, bloodsucking nematodes and larval stages of some arthropods in sheep and cattle. Its mechanism of action is through decoupling the mitochondrial oxidative phosphorylation, thus inhibiting the production of ATP. Therefore, it inhibit their energy generation of the parasite, causing their death. It is mainly used for the treatment and prevention of several infections caused by many kinds of parasites such as Fasciola hepatica, Fasciola gigantica, Haemonchus concortus, Haemonchus placei, Bunostomum phlebotomum, Oesophagostomum radiatum and Strongyloides papillosus in cattle and sheep.
| | References | http://www.interchemie.com/veterinary-medicines/closan-50.html
| | Chemical Properties | White to light yellow powder | | Uses | antianginal, antihypertensive | | Definition | ChEBI: N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide is an aromatic amide resulting from the formal condensation of the carboxy group of 3,5-diiodosalicylic acid with the amino group of aniline substituted at positions 2, 4, and 5 by methyl, (4-chlorophenyl)(cyano)methyl, and methyl groups respectively. It is a nitrile, a member of phenols, an organoiodine compound, a monocarboxylic acid amide, an aromatic amide and a member of monochlorobenzenes. |
| | Closantel Preparation Products And Raw materials |
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