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BOC Sciences
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1-631-485-4226; 16314854226 |
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Product Name:16,16-Dimethyl prostaglandin F2α
CAS:39746-23-1
Purity:>=98% Remarks:Reach out to us for more information about custom solutions.
|
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:16,16-Dimethyl prostaglandin F2α
CAS:39746-23-1
Purity:98% Package:1G;10G;100G Remarks:16,16-Dimethyl prostaglandin F2α is a metabolically stable analog of PGF2α.
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:16,16-dimethyl Prostaglandin F2α
CAS:39746-23-1
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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16,16-DIMETHYL PROSTAGLANDIN F2ALPHA manufacturers
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| | 16,16-DIMETHYL PROSTAGLANDIN F2ALPHA Basic information |
| Product Name: | 16,16-DIMETHYL PROSTAGLANDIN F2ALPHA | | Synonyms: | 16,16-DIMETHYL PROSTAGLANDIN F2ALPHA;9ALPHA,11ALPHA,15R-TRIHYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID;16,16-dimethylprostaglandin F2A;16,16-dimethyl Prostaglandin F2α;YMRWVEHSLXJOCD-SCOYTADVSA-N;Prosta-5,13-dien-1-oicacid, 9,11,15-trihydroxy-16,16-dimethyl-, (5Z,9a,11a,13E,15R)- (9CI) | | CAS: | 39746-23-1 | | MF: | C22H38O5 | | MW: | 382.53 | | EINECS: | | | Product Categories: | | | Mol File: | 39746-23-1.mol |  |
| | 16,16-DIMETHYL PROSTAGLANDIN F2ALPHA Chemical Properties |
| Fp | -13 °C | | storage temp. | -20°C | | solubility | 10 mM Na2CO3: >6.5 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: >100 mg/ml; PBS pH 7.2: >10 mg/ml | | form | A crystalline solid |
| | 16,16-DIMETHYL PROSTAGLANDIN F2ALPHA Usage And Synthesis |
| Uses | 16,16-Dimethylprostaglandin F2α (16,16-Dimethyl-PGF2α) is a potent analog of PGF2α (HY-12956), which exhibits similar binding potency as PGF2α does. 16,16-Dimethylprostaglandin F2α serves as a bronchoconstrictor[1][2]. | | in vivo | 16,16-Dimethylprostaglandin F2α (0-0.5 μg, iv, single dose) inhibits histamine-induced intracheal insufflation pressure increase in guinea pigs model. | Animal Model: | guinea pigs model[1] | | Dosage: | 0-0.5 μg | | Administration: | iv, single dose | | Result: |
Inhibited histamine-induced increase in tracheal insufflation pressure. |
| | References | [1] Strandberg K, et al., Bronchial effects of some prostaglandin E and F analogues. Acta Physiol Scand. 1977 Jun;100(2):172-81. DOI:10.1111/j.1748-1716.1977.tb05934.x
[2] Balapure AK, et al., Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2 alpha receptor. Implications for development of a photoaffinity probe. Biochem Pharmacol. 1989 Jul 15;38(14):2375-81. DOI:10.1016/0006-2952(89)90478-4 |
| | 16,16-DIMETHYL PROSTAGLANDIN F2ALPHA Preparation Products And Raw materials |
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