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2,6-Difluorobenzamide

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Products Intro: Product Name:2,6-Difluorobenzamide
CAS:18063-03-1
Purity:99% Package:25KG
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CAS:18063-03-1
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CAS:18063-03-1
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CAS:18063-03-1
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Products Intro: Product Name:2,6-Difluorobenzamide
CAS:18063-03-1
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2,6-Difluorobenzamide manufacturers

  • 2,6-Difluorobenzamide
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  • $1.00 / 200KG
  • 2024-04-25
  • CAS:18063-03-1
  • Min. Order: 200KG
  • Purity: 99%
  • Supply Ability: 20ton
  • 2,6-Difluorobenzamide
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  • $8.00 / 1KG
  • 2024-01-22
  • CAS:18063-03-1
  • Min. Order: 1KG
  • Purity: 99%
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  • 2,6-Difluorobenzamide
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  • $0.00 / 25kg
  • 2023-11-01
  • CAS:18063-03-1
  • Min. Order: 1kg
  • Purity: 98.5% min
  • Supply Ability: 10tons/month
2,6-Difluorobenzamide Basic information
Product Name:2,6-Difluorobenzamide
Synonyms:2,6-Difluorobenzamide97%;2,6-Difluorbenzamid;2,6-Difluorobenzoylamide;2,6-DIFLUOROBENZAMIDE, 98+%;Fluorine benzaMide 2, 6-2;2,6-difluoro-benzamid;2,6-DIFLUOROBENZAMIDE;2,6-difluorobenzaminde
CAS:18063-03-1
MF:C7H5F2NO
MW:157.12
EINECS:241-972-8
Product Categories:Amides;Carbonyl Compounds;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Organic Building Blocks;intermediate;Aryl Fluorinated Building Blocks;Building Blocks;C7;Carbonyl Compounds;Chemical Synthesis;Fluorinated Building Blocks;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks;18063-03-1
Mol File:18063-03-1.mol
2,6-Difluorobenzamide Structure
2,6-Difluorobenzamide Chemical Properties
Melting point 145-148 °C (lit.)
Boiling point 51-52C/15Tor
density 1,199g/cm
refractive index 1,508
storage temp. Sealed in dry,Room Temperature
solubility ethanol: soluble5%, clear to turbid, colorless to light yellow
pka14.54±0.50(Predicted)
form Solid
color Off-White
BRN 2047480
InChIKeyAVRQBXVUUXHRMY-UHFFFAOYSA-N
LogP0.011-0.25 at 25℃
CAS DataBase Reference18063-03-1(CAS DataBase Reference)
NIST Chemistry ReferenceBenzamide, 2,6-difluoro-(18063-03-1)
EPA Substance Registry SystemBenzamide, 2,6-difluoro- (18063-03-1)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-20
Safety Statements 26-37/39-36/37
WGK Germany 1
RTECS CV4355050
HazardClass IRRITANT
HS Code 29242990
Toxicityrat,LC50,inhalation,> 2100mg/m3/4H (2100mg/m3),National Technical Information Service. Vol. OTS0543293,
MSDS Information
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2,6-Difluorobenzamide English
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2,6-Difluorobenzamide Usage And Synthesis
Description2,6-Difluorobenzamide is a major metabolite of pesticide diflubenzuron and has been quantitated by HPLC/diode-array method.
Description2,6-Difluorobenzamide is a white powdery crystal, insoluble in water. It can be obtained by hydrolysis of 2,6-difluorobenzonitrile. 2,6-Difluorobenzamide is an important intermediate in the synthesis process of benzoylurea insecticides, which is used to synthesize the next intermediate 2,6-difluorobenzoyl isocyanate, and finally obtain flubolurea, pyruron, fluridin, lice mite urea and other pesticide varieties. It can also be directly used to synthesize pyruron and flubolea. 2,6-Difluorobenzamide can inhibit the bacterial cell division protein FtsZ[1].
Chemical Propertieswhite to yellowish powder
Uses2,6-Difluorobenzamide (CAS# 18063-03-1) is a useful building block used in the synthesis of (E)-3-methyleneisoindolin-1-ones via oxidative annulation acrylates. It is also used in the synthesis of pesticide intermediates, which can be used to produce various insecticides such as fluazuron, chlorpyrifos, and pyrethroids.
Preparation2,6-Difluorobenzamide is obtained by hydrolysis of 2,6-difluorobenzonitrile.
References[1] Straniero V, et al. 2,6-Difluorobenzamide inhibitors of the bacterial cell division protein FtsZ: design, synthesis and Structure Activity Relationship study. ChemMedChem, 2017; 12: 1303-1318.
Tag:2,6-Difluorobenzamide(18063-03-1) Related Product Information
2,6-Difluorobenzonitrile p-Aminobenzamide Chlorantraniliprole 2,6-Difluorobenzoic acid Benzamide 3,5-DIFLUOROBENZAMIDE 2,3,6-TRIFLUOROBENZAMIDE 2,3,4,5,6-PENTAFLUOROBENZAMIDE N-PENTAFLUOROBENZOYLIMIDAZOLE 4-AMINO-2,3,5,6-TETRAFLUOROBENZAMIDE Diflubenzuron Chlorfluazuron 2,6-Difluorobenzoyl hydrazine Teflubenzuron 2-CHLORO-3,6-DIFLUOROBENZAMIDE 3-CHLORO-2,6-DIFLUOROBENZAMIDE Difluorochloromethane 2,5-DIFLUOROBENZAMIDE