GSK-656 manufacturers
- Ganfeborole HCl
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- $199.00 / 1mg
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2025-09-30
- CAS:2131798-13-3
- Min. Order:
- Purity: 99.88%
- Supply Ability: 10g
- Ganfeborole HCl
-
- $199.00 / 1mg
-
2025-09-30
- CAS:2131798-13-3
- Min. Order:
- Purity: 99.88%
- Supply Ability: 10g
- GSK-656
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- $15.00 / 1KG
-
2021-07-02
- CAS:2131798-13-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | GSK-656 Basic information |
| Product Name: | GSK-656 | | Synonyms: | GSK-656;GSK-3036656;GSK656 HCl;GSK656 HCl (GSK3036656, GSK070);GSK656,GSK-656;Ganfeborole hydrochloride;GSK656 hydrochloride;Ganfeborole HCl | | CAS: | 2131798-13-3 | | MF: | C10H14BCl2NO4 | | MW: | 293.94 | | EINECS: | | | Product Categories: | | | Mol File: | 2131798-13-3.mol |  |
| | GSK-656 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO:67.5(Max Conc. mg/mL);229.64(Max Conc. mM) | | form | Solid | | color | Off-white to light yellow |
| | GSK-656 Usage And Synthesis |
| Uses | Ganfeborole hydrochloride (GSK656) is a potent antitubercular agent, acting as an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS), with an IC50 of 0.2 μM. | | in vivo | Ganfeborole hydrochloride shows potent antitubercular activity in mice infected with M. tuberculosis H37Rv, with ED99 of 0.4 mg/kg[1]. | | References | [1] Li X, et al. Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656). J Med Chem. 2017 Oct 12;60(19):8011-8026. DOI:10.1021/acs.jmedchem.7b00631 |
| | GSK-656 Preparation Products And Raw materials |
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