- TH34
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- $9.80 / 1.79999995231628KG
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2020-01-09
- CAS:2196203-96-8
- Min. Order: 1g
- Purity: ≥99%
- Supply Ability: 100kg
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Product Name: | TH34 | Synonyms: | TH34;CS-2858;TH34;TH 34;3-(Benzylamino)-N-hydroxy-4-methylbenzamide;TH34,inhibit,Inhibitor,TH 34,TH-34,HDAC,Histone deacetylases;Benzamide, N-hydroxy-4-methyl-3-[(phenylmethyl)amino]- | CAS: | 2196203-96-8 | MF: | C15H16N2O2 | MW: | 256.3 | EINECS: | | Product Categories: | | Mol File: | 2196203-96-8.mol | |
density | 1.236±0.06 g/cm3(Predicted) | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | solubility | DMSO : 150 mg/mL (585.25 mM) | pka | 9.04±0.10(Predicted) |
Biological Activity | TH34 is an HDAC6/8/10 inhibitor with IC50 values of 4.6 μM, 1.9 μM and 7.7 μM, respectively, showing high selectivity compared with HDAC1/2/3. | in vitro | TH34 induces caspase-dependent programmed cell death and cell cycle arrest in neuroblastoma cells. | target | HDAC6 4.6 μM (IC 50 ) | HDAC8 1.9 μM (IC 50 ) | HDAC10 7.7 μM (IC 50 ) | |
| TH34 Preparation Products And Raw materials |
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