Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem
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Company Name: |
Riedel-de Haen AG
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Tel: |
800 558-9160 |
Email: |
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Products Intro: |
Product Name:Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem
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| Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem Basic information |
| Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem Chemical Properties |
| Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem Usage And Synthesis |
General Description | A potent, cell-permeable, and metabolically stable inhibitor of protein kinase G (PKG; Ki = 4 μM). Acts as a cyclic nucleotide-gated channel agonist (EC50 = 173.5 μM). Significantly more lipophilic and membrane-permeable than cGMP or Rp-cGMPS. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Note: 5 μmol = 2.31 mg. | Biochem/physiol Actions | Cell permeable: yes |
| Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem Preparation Products And Raw materials |
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