4-Nitrobenzyl bromide

4-Nitrobenzyl bromide Basic information

Product Name:	4-Nitrobenzyl bromide
Synonyms:	4-Nitrobenzyl bromide, 97+%;4-nitrobenzyl bormide;4-Nitrobenzyl;Benzene, 1-(bromomethyl)-4-nitro-;à-bromo-4-nitrotoluene;4-Nitrobenzyl bromide 98%;BROMOMETHYL-4-NITROBENZENE;p-NITROBENZYL BROMIDE pure
CAS:	100-11-8
MF:	C7H6BrNO2
MW:	216.03
EINECS:	202-820-6
Product Categories:	Pyridines;Building Blocks;Chemical Synthesis;Nitro Compounds;Nitrogen Compounds;Organic Building Blocks;Aromatic Halides (substituted);Methyl Halides;Phenyls & Phenyl-Het;Protection & Derivatization Reagents (for Synthesis);Synthetic Organic Chemistry;Methyl Halides;Phenyls & Phenyl-Het
Mol File:	100-11-8.mol

4-Nitrobenzyl bromide Chemical Properties

Melting point	98 °C
Boiling point	265.51°C (rough estimate)
density	1.6841 (rough estimate)
refractive index	1.6120 (estimate)
storage temp.	Store at RT.
solubility	soluble in Chloroform, Ethyl Acetate
form	Crystalline Powder
color	Light yellow to beige
Water Solubility	It hydrolyzes in water. Soluble in alcohol and ether.
BRN	742796
Stability:	Stable. Incomaptible with bases, amines, oxidizing agents, alcohols. May be moisture sensitive. Corrodes steel.
CAS DataBase Reference	100-11-8(CAS DataBase Reference)
NIST Chemistry Reference	Benzene, 1-(bromomethyl)-4-nitro-(100-11-8)
EPA Substance Registry System	Benzene, 1-(bromomethyl)-4-nitro- (100-11-8)

Safety Information

MSDS Information

4-Nitrobenzyl bromide Usage And Synthesis

Chemical Properties	white to light yellow crystal powde
Uses	4-Nitrobenzyl bromide is used in the synthesis of di and tri-substituted azoles. It is also used in the preparation of N6-Benzyladenosine-5?-uronamides as selective A3 adenosine agonists.
Definition	ChEBI: A C-nitro compound that consists of nitrobenzene bearing a bromomethyl substituent at the para-position.
Purification Methods	Recrystallise the bromide four times from absolute EtOH, then twice from cyclohexane/hexane/*benzene (1:1:1), followed by sublimation at 0.1mm and final recrystallisation from the same solvent mixture. [Lichtin & Rao J Am Chem Soc 83 2417 1961.] It has also been crystallised from pet ether (b 80-100o, 10mL/g, charcoal). It slowly decomposes even when stored in a desiccator in the dark. IRRITANT. [Beilstein 5 IV 861.]

4-Nitrobenzyl bromide Preparation Products And Raw materials

Raw materials	4-Nitrotoluene
Preparation Products	FLUCYCLOXURON-->4-(Morpholinomethyl)aniline-->DIETHYL(4-NITROBENZYL)PHOSPHONATE-->2-Nitro-3-pyridinamine-->N,N-DIBENZYL GLYCINE METHYL ESTER-->1-(4-Nitrophenyl)methyl-1,2,4-triazole-->(4-Nitrophenyl)methanesulfonyl chloride-->4-Aminobenzylamine-->4-AMINO-N,N-DIMETHYLBENZYLAMINE

Tag:4-Nitrobenzyl bromide(100-11-8) Related Product Information

4-Cyanobenzyl bromide 4-Nitrobenzenesulfonyl chloride 4-Nitrobenzyl chloroformate 4-Nitrophenol 4-Nitrotoluene Sodium bromate Rocuronium bromide (4-Nitrophenyl)methyl 3-oxobutanoate BRETYLIUM TOSYLATE Dimidium bromide Benzyl bromide Vecuronium bromide 4-Nitrobenzoic acid 4-Nitrobenzonitrile 4-Nitrobenzyl alcohol Allyl bromide Ethidium bromide 4-Nitrobenzyl chloride

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