| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Products Intro: |
Product Name:Monoclonal Anti-EP300 antibody produced in mouse
|
| Company Name: |
Riedel-de Haen AG
|
| Tel: |
800 558-9160 |
| Email: |
|
| Products Intro: |
Remarks:clone 1D2, purified immunoglobulin, buffered aqueous solution
|
| Company Name: |
Alexis Corporation
|
| Tel: |
+41 61 926 8989 |
| Email: |
alexis-ch@alexis-corp.ch |
| Products Intro: |
|
| Company Name: |
Nacalai Tesque, Inc.
|
| Tel: |
81 75 251 1723 |
| Email: |
info-tech@nacalai.co.jp |
| Products Intro: |
|
| Company Name: |
Upstate
|
| Tel: |
434 975 4300 |
| Email: |
info@upstate.com |
| Products Intro: |
|
|
| | ANTI-P300 Basic information |
| Product Name: | ANTI-P300 | | Synonyms: | P300 (AB-1) MONOCLONAL ANTIBODY;Monoclonal Anti-EP300 antibody produced in mouse;ANTI-HUMAN P300;ANTI-P300 CT;ANTI-P300, HUMAN;ANTI-P300(AB-1);ANTI-P300 MOUSE MAB;ANTI-P300 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-P300 Structure]() |
| | ANTI-P300 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | mouse |
| | ANTI-P300 Usage And Synthesis |
| Biological Activity | E1A binding protein p300 (p300) and CBP (CREB binding protein) are highly related transcriptional coactivators. Both proteins have been identified through protein interaction assays. In addition to interacting with a variety of cellular factors and oncoproteins, loss of the wild type CBP alleles in isolated tumors suggests th at CBP/p300 might serve as tumor suppressors. The ability of p300 to acetylate many transcription factors, including tumor suppressor p53, E2 factor (E2F), transcription factors II E and -F (TFIIE and -F) etc. demonstrates a novel mechanism of targeted p300 regulation of gene expression. Mutations in the gene encoding the protein have been linked to Rubinstein-Taybi syndrome (RSTS). |
| | ANTI-P300 Preparation Products And Raw materials |
|