- 4-Phenoxybenzylamine
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- $64.00 / 500mg
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2025-06-13
- CAS:107622-80-0
- Min. Order:
- Purity: ≥95%
- Supply Ability: 10g
- 4-PHENOXYBENZYLAMINE
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- $2.00 / 1kg
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2019-07-06
- CAS:107622-80-0
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100kg
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| | 4-PHENOXYBENZYLAMINE Basic information |
| | 4-PHENOXYBENZYLAMINE Chemical Properties |
| Boiling point | 138°C 5mm | | density | 1,12 g/cm3 | | refractive index | 1.59 | | Fp | 150℃ | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Soluble in DMSO | | form | clear liquid | | pka | 9.13±0.10(Predicted) | | color | Colorless to Light orange to Yellow | | CAS DataBase Reference | 107622-80-0(CAS DataBase Reference) |
| | 4-PHENOXYBENZYLAMINE Usage And Synthesis |
| Uses | 4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against FL NS3/4a. | | Biological Activity | 4-Phenoxybenzylamine inhibits the function of NS3 protein by stabilizing the inactive conformation, and inhibits FL NS3/4a with an IC50 value of approximately 500 μM. | | in vitro | A highly conserved novel binding site located at the interface between the protease and helicase domains of the Hepatitis C Virus (HCV) NS3 protein is identified. 4-Phenoxybenzylamine binding at this allosteric site inhibits the function of the NS3 protein by stabilizing an inactive conformation and thus represents a new class of direct acting antiviral agents. | | target | | | References | [1] Saalau-Bethell SM, et al. Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function. Nat Chem Biol. 2012 Nov;8(11):920-5. DOI:10.1038/nchembio.1081 |
| | 4-PHENOXYBENZYLAMINE Preparation Products And Raw materials |
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