| Company Name: |
Wuxi AppTec |
| Tel: |
022-59987777 13552403979 |
| Email: |
jia_guoqiang@wuxiapptec.com |
| Company Name: |
3A Chemicals |
| Tel: |
400-668-9898 |
| Email: |
service@3achem.com |
Methyl 2 3-butadienoate manufacturers
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| | Methyl 2 3-butadienoate Basic information |
| | Methyl 2 3-butadienoate Chemical Properties |
| Melting point | 115 °C(Solv: benzene (71-43-2)) | | Boiling point | 59-60 °C(Press: 52 Torr) | | density | 0.905±0.06 g/cm3(Predicted) | | form | liquid | | color | colorless |
| | Methyl 2 3-butadienoate Usage And Synthesis |
| Uses | Methyl 2,3-Butadienoate is used as an reactive electrophilic reagents for nucleophilic addition, Michael addition, [2 + 2], [2 + 3], and
[2 + 4] cycloadditions, and hetero-Cope rearrangements. | | Preparation | Methyl 2,3-Butadienoate is most conveniently obtained via a Wittig reaction of [E(R)CHPPh3]+X- or
E(R)C=PPh3 and RR′CHCOCl (R, R′ = H, alkyl) in the presence of Triethylamine in CH2Cl2.[1]Alternatively, the Wittig reaction can be performed with the corresponding ketenes.[2] | | Synthesis Reference(s) | Tetrahedron Letters, 13, p. 4249, 1972 DOI: 10.1016/S0040-4039(01)94287-X | | storage | Methyl 2,3-Butadienoate can undergo polymerization and so should be stored in the presence
of hydroquinone. For best results, it should be freshly distilled. Use in a fume hood. | | Purification Methods | Purification of Methyl 2,3-Butadienoate: rapid distillation under reduced pressure in a short-path distillation apparatus or column
chromatography on Alox N with hexane/Et2O (9:1). Hydroquinone may be added for distillation. | | References | 1. (a) Lang, R. W.; Hansen, H.-J. HCA 1980, 63, 438. (b) Lang, R. W.; Hansen, H.-J. OS 1984, 62, 202
2. Hamlet, Z.; Barker, W. D. S 1970, 543.
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| | Methyl 2 3-butadienoate Preparation Products And Raw materials |
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