ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE manufacturers
- Sp-cAMPS
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- $1980.00 / 50mg
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2025-10-27
- CAS:71774-13-5
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE Basic information |
| Product Name: | ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE | | Synonyms: | adenosine-3’,5’-cyclicmonophosphorothioate,sp-isomer(sp-camps),sodiumsalt;camps,sp-isomer,teasalt;ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE;(S)-Adenosine;cAMPS-Sp;Triethylammoniumsalt;(S)-ADENOSINE, CYCLIC 3',5'-(HYDROGENPHOSPHOROTHIOATE) TRIETHYLAMMONIUM;ADENOSINE3,5-CYCLICMONOPHOSPHOTHIOATESP-ISOMERTRIETHYLAMMONIUMSALT,HIGHPURITY | | CAS: | 71774-13-5 | | MF: | C10H12N5O5PS | | MW: | 345.27 | | EINECS: | | | Product Categories: | Cyclic Nucleotide related | | Mol File: | 71774-13-5.mol |  |
| | ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE Chemical Properties |
| Boiling point | 648.0±65.0 °C(predicted) | | density | 2.38±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | storage temp. | Desiccate at -20°C | | pka | -0.55±0.60(predicted) | | form | crystalline solid | | Water Solubility | water: 20mg/mL |
| | ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE Usage And Synthesis |
| Uses | (S)-Adenosine, cyclic 3'',5''-(hydrogenphosphorothioate) triethylammonium is an activator of PKA. | | Definition | ChEBI: (Sp)-cAMPS is a nucleoside 3',5'-cyclic phosphorothioate having adenine as the nucleobase (the Sp-stereoisomer). It has a role as a protein kinase agonist. It is a member of purines and a nucleoside 3',5'-cyclic phosphorothioate. It is functionally related to a 3',5'-cyclic AMP. | | Biological Activity | Cell-permeable cAMP analog that activates cAMP receptor proteins such as PKA and cAMP-regulated guanine nucleotide exchange factor. | | in vivo | In chronic alcohol consumption (CAC) mice, direct infusion of the Sp-cAMPS (1 μg/μL) into the prefrontal cortex significantly improves or impairs, respectively, working memory performance in withdrawn and water animals[5]. | | IC 50 | PKA I; PKA II; PDE3A: 47.6 μM (Ki); PDE10 GAF domain: 50 μM (EC50) |
| | ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE Preparation Products And Raw materials |
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