| Company Name: |
GeneTex, Inc. |
| Tel: |
0755-26755892 1-949-553-1900 |
| Email: |
international@genetex.com |
| Company Name: |
NSJ Bioreagents |
| Tel: |
858.663.9055 8586639055 |
| Email: |
NSJBioname@qq.com |
| Company Name: |
Enzo Biochem Inc |
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Email: |
Enzoname@qq.com |
|
| | PLA2G1B Antibody Chemical Properties |
| | PLA2G1B Antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human | | Background | Phospholipase A2 is a superfamily of enzymes that hydrolyze glycero-3-phosphocholines and release fatty acids and lysophospholipids. PLA2G1B is a member of this superfamily in the 1B group that is expressed most highly in the pancreatic acinar cells. Evidence suggests that PLA2G1B plays a role in the absorption and storage of extra energy as fats are metabolized. Lysophospholipids generated by PLA2G1B inhibit fatty acid oxidation in the liver and reduce energy expenditure, leading to diet-induced obesity and type 2 diabetes with a high fat diet. Therefore, a potential intervention of obesity and diabetes could target PLA2G1B in the digestive tract. | | References | [1] Labonté, E.D. et al. (2010) FASEB J 24, 2516-24.
[2] Cash, J.G. et al. (2011) Int J Obes (Lond) 35, 877-81. |
| | PLA2G1B Antibody Preparation Products And Raw materials |
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