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| | Schisandrin A Basic information |
| | Schisandrin A Chemical Properties |
| Melting point | 116-117 °C | | Boiling point | 544.2±50.0 °C(Predicted) | | density | 1.080±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | powder | | color | White to Off-White | | LogP | 5.870 (est) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | RTECS | HP1595000 | | HS Code | 29093090 |
| | Schisandrin A Usage And Synthesis |
| Description | Schisandrin A is a lignan that has been found in Schisandra and has diverse biological activities. It binds to adiponectin receptor 2 (IC50 = 3.2 μM). Schisandrin A (10, 20, and 50 μM) reduces LPS-induced production of nitric oxide (NO), IL-6, and TNF-α and apoptosis in primary mouse microglial cells. It reverses P-glycoprotein-mediated doxorubicin resistance in MCF-7/dox cells when used at a concentration of 20 μM. Schisandrin A (4, 12, and 36 mg/kg) reverses short-term and spatial memory deficits, as well as decreases in cerebral superoxide dismutase (SOD) and glutathione peroxidase (GPX) activities induced by amyloid β (1-42) (Aβ42; ) in a mouse model of Alzheimer’s disease. | | Chemical Properties | White powder | | Uses | Schizandrin A is an extract from Schisandra chinesis. a dibenzocyclooctadiene lignan with antiinflammatory activity. |
| | Schisandrin A Preparation Products And Raw materials |
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